Skin cancer, chemoprevention, phytochemicals, topical applicationSkin cancer is the most common malignancy. Its pathogenesis is a multi-step, cumulative process which allows for potential intervention along the length of its spectrum. Cancer chemoprevention is a very promising approach to obtaining this ...
The side effects associated with oral sirolimus are commonly difficult to manage and usually result in withdrawal of the drug. These include acne, albuminuria, mouth ulceration, oedema, rash, and pneumonitis. Despite poor tolerance, the benefit oral sirolimus achieved in reducing skin cancer ...
4d). Excitingly, these findings indicate that the topical application of SMPs alters the skin and the chemo-attraction of immune cells from systemic responses following skin injury. SMP intervention increases superoxide dismutase activity after NM-induced injury Skin injury leads to the excessive ...
J. Cancer Chemoprev. 9, 92–101 (2018) Google Scholar D. Montesano, F. Blasi, M.S. Simonetti, A. Santini, L. Cossignani, Foods 7, 30 (2018) PubMed Central Google Scholar M.R. Al-Sereiti, K.M. Abu-Amer, P. Sena, Indian J. Exp. Biol. 37, 124–131 (1999) CAS PubMed...
These findings suggest a potential dual therapeutic strategy: direct Anti-proliferative Effect of ADA and Chemo-sensitization of doxorubicin by ADA. Similarly, they investigated the synergistic therapeutic combination GDC-0941 and Adapalene in BC using repurposed medications [48]. The findings showed ...
J Natl Cancer Inst 110(2) Starobova H, Vetter I (2017) Pathophysiology of chemotherapy-induced peripheral neuropathy. Front Mol Neurosci 10:174 Article PubMed PubMed Central Google Scholar Gießen-Jung C, von Baumgarten L (2018) Chemotherapie-induzierte periphere Neuropathie [Peripheral ...
Evozac® Calming Skin Spray (Evaux Laboratories, Évaux-les-Bains, France) is made of Évaux thermal spring water, which is naturally rich in lithium. It is commonly used to manage dermatological toxicities caused by chemo- therapy, radiation therapy, and anti-EGFR therapy in several ...
For example, topical application of corticosteroids usually causes skin irritation, and the treatment is often compromised due to low drug retention and penetration [11]. As for phototherapy, the anti-psoriasis therapeutic outcome is always delayed, and the risk of skin cancer also restrains its ...
Imiquimod is a topically active immunomodulatory agent that is formulated as a 5% cream for application by the patient. It is the first agent of its class,
Bonavida et al., Novel therapeutic applications of nitric oxide donors in cancer: roles in chemo- and immunosensitization to apoptosis and inhibition of metastases. Nitric Oxide. Sep. 2008;19(2):152-7. Epub Apr. 24, 2008. Brandl et al., Morphology of semisolid aqueous phosphatidylcholine ...