Topical antifungal treatment prevents recurrence of toenail onychomycosis following cureefficacyprophylaxistinea unguiumBackground: Despite the fact that lasers are presently indicated for the cosmetic outcome "temporary increase in clear nail", these devices are increasingly used to treat onychomycosis and ...
Efinaconazole 10% topical solution is a new antifungal therapy for the topical treatment of mild to moderate toenail onychomycosis. In vitro and in vivo data have shown significant antifungal activity against dermatophytes, Candida spp. and nondermatophyte molds, and its mechanism of action is thr...
1. Indications and Usage for Tavaborole Topical Solution Tavaborole topical solution, 5% is an oxaborole antifungal indicated for the treatment of onychomycosis of the toenails due to Trichophyton rubrumor Trichophyton mentagrophytes. 2. Tavaborole Topical Solution Dosage and Administration Apply tavaborole...
The authors' nonclinical study using a cadaver nail model showed that penetration of efinaconazole topical solution, 10%, a new antifungal being developed for the treatment of mild-to-moderate toenail onychomycosis, was not influenced by application of nail polish. Polishes showed an increase in ...
Acidic and propionic (propanoic) acids are known to have antifungal properties, particularly against pseudomonas aeruginosa, candida and aspergillus strains. The use of these acids for the treatment of nail fungal diseases, however, has not been effective as these acids cannot be safely applied to ...
The results of the use of terbinafine 3% gel in treatment of onychomycosis of the toenail were obtained from an open label study. In this study, patients with onychomycosis were treated with terbinafine 3% gel or vehicle only for 42 days. The day 42 study results showed that 39.3% of the ...
such as chemical modification of antifungal agents, carrier-based delivery using penetration enhancers, preparation and application of nanoformulations, and combined treatment with physical methods to enhance drug delivery, including iontophoresis, photodynamic therapy, and lasers (Dutet & Delgado-Charro, Ci...
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Article: Fractional carbon dioxide laser assisted delivery of topical tazarotene versus topical tioconazole in the treatment of onychomycosis
Bhatt V., Pillai R. Efinaconazole topical solution, 10%: formulation development program of a new topical treatment of toenail onychomycosis. Journal of Pharmaceutical Sciences . 2015; 104 (7):2177–2182. doi: 10.1002/jps.24459. [ Cross Ref ]...