7. Kohei Nakachi, et al. Hepatobiliary and Pancreatic Oncology Group of the Japan Clinical Oncology Group, A randomized Phase III trial of adjuvant S-1 therapy vs. observation alone in resected biliary tract cancer: Japan Clinical Oncology Group Study (JCOG1202, ASCOT), Japanese Journal of Clin...
7. Kohei Nakachi, et al. Hepatobiliary and Pancreatic Oncology Group of the Japan Clinical Oncology Group, A randomized Phase III trial of adjuvant S-1 therapy vs. observation alone in resected biliary tract cancer: Japan ...
It was attempted in biliary [cancer] because the effects of stimulation of PD-1 and PD-L1 inhibitor are very modest at best. That’s the loose rationale that went into this combination. I’m very happy that it led to significant clinical benefit and now 2 studies in the frontline setting...
Conclusions: In TOPAZ-1, characteristics of LTS were generally consistent with the FAS. Overall, LTS were more common with D + GC; LTS in the PBO + GC group appear to be associated with higher frequency of subsequent treatments, including immunotherapy. Clinical trial information: NCT03875235 ....
Articles: 1 This clinical trial was just registered: Ultrasound-guided Pulsed Radiofrequency for Plantar Fasciitis Although there are many conservative method for plantar fasciitis, patients might spend 2 years to achieve resolution. Recent study have shown that pulsed radiofrequency (PRF) lesioning of...
EP: 1.Prognosis and Standards of Care in Advanced Biliary Tract Cancer EP: 2.Discussion of a Patient Case of Advanced BTC EP: 3.Homing in on the TOPAZ-1 Trial in Biliary Tract Cancer Now Viewing EP: 4.Putting TOPAZ-1 Data into Context for Patients With Advanced BTC EP: 5.Clinical Imp...
(2) that there were no safety concerns and that BioAge expected top line results and to meet its primary endpoint goals in connection with its STRIDES clinical trial; and (3) as a result, Defendants' sta...
Clinical results improve with time for up to 1-year post-operatively. The open method seems to have a more significant improvement in pain VAS scores at 1-year postoperatively. 展开 关键词: Plantar fasciitis TOPAZ Radiofrequency microtenotomy Percutaneous Minimally invasive ...
Clinical trial information: NCT03875235.HRs for median TTD (HR [95% CI]/p-value; HR <1 favors D + GC). C30 functioning: Physical Role Cognitive Emotional Social 1.05 [0.83–1.35]/0.678 1.08 [0.85–1.36]/0.558 1.09 [0.86–1.39]/0.487 0.98 [0.75–1.30]/0.914 0.98 [0.77–1.25]/0.865 ...
Aiming to enroll 3,500 participants age 65 years or older, TOPAZ is one of the largest randomized, placebo-controlled clinical trials ever attempted in parkinsonism. The feasibility of TOPAZ is enhanced by its design as a U.S.- wide home-based trial without geographical limits. Participants ...