英文名称: Tolvaptan Tablets 【成分】本品主要成份是托伐普坦。化学名称:(±)-4'-[(7-氯-2,3,4,5-四氢-5-羟基-1H-1-苯并杂氮卓-1-基)羰基]-N-邻-甲苯酰基-间-苯甲胺。 【性状】本品为蓝色片 【适应症】 1.低钠血症 用于治疗临床上明显的高容量性和正常容量性低钠血症(血清钠浓度<125mEq/...
托伐普坦片Tolvaptan-详细说明书与重点.docx,托伐普坦片Tolvaptan 英文名称: Tolvaptan Tablets 【成分】 本品主要成份是托伐普坦。 化学名称:(±)-4-[(7-氯-2,3,4,5-四氢-5-羟基-1H-1-苯并杂氮卓-1-基)羰基]-N-邻-甲苯酰基-间-苯甲胺。 【性状】 本品为蓝色片 【适应症】
reduced with tin(II) chloride. This aniline is coupled with 2-methylbenzoyl chloride to give the penultimate intermediate. In the final step, reduction of the ketone functionality with sodium borohydride provides racemic tolvaptan that is formulated into 15- and 30-mg tablets for oral administration...
The aims were to evaluate multiple-dose pharmacokinetics, pharmacodynamics and safety of daily administration of 15 mg tolvaptan in Chinese adult patients with confirmed Child-Pugh Class B cirrhosis accompanied by ascites. Methods: This was an open-label, single-center, single...
In the final step, reduction of the ketone functionality with sodium borohydride provides racemic tolvaptan that is formulated into 15- and 30-mg tablets for oral administration. The pharmacokinetics of tolvaptan have been evaluated in healthy individuals. While the AUC increases proportionally with ...
欧盟HMA上市药品数据库提供Tolvaptan AbZ 15 mg Tabletten药品的基本信息,包括通用名tolvaptan,中文名托伐普坦,ATC代码C03XA01 tolvaptan以及上市许可持有人ratiopharm GmbH Graf-Arco-Str. 3 89079 Ulm Deutschland等信息的查询.
DMSO: ≥15mg/mL 2.9 Stability Stable under recommended storage conditions. 2.10 StorageTemp 2-8°C 2.11 Toxicity Summary IDENTIFICATION AND USE: Tolvaptan; is a white crystalline powder that is formulated into oral tablets. Tolvaptan; is an antagonist of arginine vasopressin; (antidiuretic hormone)...
[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide; N-[4-[(5R)-7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide; Tolvaptan; OPC 41061; OPC-41061; SaMsca; Tolvaptan Tablets; N-(4-(7-Chloro-5-hydroxy-2,...
根据印度全球药房网站,印度Sunrise生产的托伐普坦(Tolvaptan Tablets)一盒(15mg4片或30mg4片)的售价为800元人民币。这个价格可能随汇率或其他原因波动,仅供参考。 如果您有需要,可以联系泰必达客服,我们是一家专业的医药咨询公司,可以为您提供药品渠道咨询、海外就医咨询、医学顾问服务等。请扫描或点击下方的客服二维...
部份中文托伐普坦处方资料(仅供参考)商品名:Jinarc英文名:Tolvaptan tablets中文名:托伐普坦薄膜片生产商:大冢制药药品简介2015年6月1日,日本大冢制药为其治疗成年人常染色体显性多囊肾病 (ADPKD)的药物托伐普坦(Jinarc)获得欧盟上市许可。这款药物旨在用于初始治疗后有证明显示疾病快速进展的慢性肾病(CKD)处于1-3...