action, and contraindications for tolterodine as a valuable agent in treating overactive bladder. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off
© 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved. tolterodine Detrol, Detrol LA, Detrusitol (UK), Detrusitol XL (UK) Pharmacologic class: Anticholinergic Therapeutic class: Urinary tract antispasmodic Pregnancy risk category C Action Competitively antagonizes muscarinic ...
The main effects of tolterodine at 1 and 5 hours were an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure. These findings are consistent with an antimuscarinic action on the lower urinary tract. Pharmacokinetics Absorption In a ...