2009 . Csm3, Tof1, and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks. J Biol Chem 284:34355–34365.Bando M, et al .: Csm3, Tof1, and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks. J Biol Chem 2009, 284 (...
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By modulating each of these functions independently, we rule out that one of these known replication roles explains the contribution of Tof1-Csm3 and Mrc1 to cohesion establishment. Instead, using purified components, we reveal direct and multipronged protein interactions of Tof1-Csm3 and Mrc1 ...
The Mrc1, Tof1 懈 Csm3 are found to be nuclear proteins with specific role in the replication of DNA and the S-phase chekpoint. They form a complex that associates with the replication fork. Recent studies demonstrated that this complex has a role in the regulation of the replicative ...
S. (2005) Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex. J. Mol. Biol., 347, 509-521.Nedelcheva MN, Roguev A, Dolapchiev LB, Shevchenko A, Taskov HB, Stewart AF, Stoynov SS (2005) Uncoupling of unwinding from DNA ...