In order to measure the peak level, a serum sample should be drawn about 30 minutes following intravenous infusion or 1 hour after an intramuscular injection Trough levels are measured by obtaining serum samples at 8 hours or just prior to next dose; these suggested time intervals are intended...
Peak urine concentrations ranging from 75 to 100 mcg/mL have been observed following the intramuscular injection of a single dose of 1 mg/kg. After several days of treatment, the amount of tobramycin excreted in the urine approaches the daily dose administered. When renal function is impaired, ...
11 patients with moderate infections were treated with bolus injections of tobramycin in a fixed dose of 4.5 mg/kg and day for 8 days. The patients were randomized to injections every 8 h (TID) for 4 days followed by injection every 12 h (BID) or vice versa. Serum concentrations were ...
Each single-dose 5 mL ampule contains 300 mg tobramycin and 11.25 mg sodium chloride in sterile water for injection. Sulfuric acid and sodium hydroxide are added to adjust the pH to 6.0. Nitrogen is used for sparging. All ingredients meet USP requirements. The formulation contains no preservative...
Heparin Sodium Injection - USP:肝素钠注射液-美国药典 热度: 硫酸妥布霉素注射液的缓释制剂研究 热度: concentrationsaredependentondose,rateofpenetration,anddegreeofmeningealinflammation.Ithasalsobeenfoundinsputum,peritonealfluid,LowerrespiratorytractinfectionscausedbyP.aeruginosa,Klebsiellaspp,Enterobacterspp,Serratia...
Higher concentrations (10–12 mg/L) have been obtained by bolus injection over about 3 min. Peak concentrations of around 50 mg/L have been reported in cystic fibrosis patients given 9 mg/kg once daily. Ten minutes after a 300 mg dose of tobramycin solution for inhalation, mean ...
Clindamycinis the 7(S)-chlorodeoxylincomycin derivative.Pirlimycinis the 4-cis-ethyl-l-pipecolic derivative of clindamycin. For oral use, apalmitatesalt of clindamycin hydrochlorine is available; for injection,clindamycin phosphateis available.33 ...
Do not take Nebcin injection if you are allergic to tobramycin or any ingredients contained in this drug Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately Contraindications ...
[4] Dosage: 7.5,15,30,120,441,969 mg/kg Administration: Subcutaneous injection (s.c.), Intravenous injection (i.v.) ,Intramuscular injection(i.m.) Result: The s.c. LD50 values in mice and rats were 441 and 969 mg/kg, respectively. Within 1 hour after treated, death with central ...
部份中文妥布霉素处方资料(仅供参考)英文名:tobramycin商品名:Tobi Inhalationslösung中文名:妥布霉素喷雾器吸入溶液生产商:Mylan Pharma GmbH药品简介妥布霉素(tobramycin)吸入液剂(TOBI)获欧盟许可,用于长期治疗囊性纤维化病人铜绿假单胞菌引起的慢性肺部感染,并获得许可用于6岁以上儿童。适应症1.主要用于假单孢菌...