Shedding of TNFR1 in regenerative liver can be induced with TNF alpha and PMA. World J Gastroenterol. 2002; 8:1129-1133.XIA M,XUE S B,XU C S.Shedding of TNFR1 inregenerative liver can be induced with TNFαandPMA. World J Gastroeenterol . 2002Xia M,Xue SB,Xu CS. Shedding of TNF...
Positive IF-P detected in human liver cancer tissue For other applications, we recommend the unconjugated version of this antibody, 60192-1-Ig 推荐稀释比 ApplicationDilution Immunofluorescence (IF)-P IF-P : 1:50-1:500 It is recommended that this reagent should be titrated in each testing syste...
TNFR1 signaling in various diseases is receiving increasing attention. TNFR1-mediated signaling pathways are crucial in the pathogenesis of diseases such as autoimmune disorders, chronic inflammatory diseases, and cancer. Currently, several anti-TNF-α therapies are available for diseases such as rheumato...
TNFR1 signaling in various diseases is receiving increasing attention. TNFR1-mediated signaling pathways are crucial in the pathogenesis of diseases such as autoimmune disorders, chronic inflammatory diseases, and cancer. Currently, several anti-TNF-α therapies are available for diseases such as rheumato...
Normal tissue complication probability (NTCP) models that account for MLD have been developed in an effort to minimize risks of therapy, though these models are limited by the assumption that all liver tissue contributes equally to liver function [6,7]. Unfortunately, patients with primary hepatic...
Casp8−/− Tnfr1−/− embryos had more ZBP1+ cells than WT or Tnfr1−/− embryos, with myeloid infiltrates in the liver and vessels being labeled (Fig. 5a, b, d). Myeloid aggregates in the Casp8−/− Tnfr1−/− liver included F4/80+ macrophages (Fig. 5e). No ...
Although PGE 1 enhanced and anti-TNF-α reduced TNF-α concentration in serum, both protective treatments reduced the expression of TNF-R1 in hepatocytes. TNF-R2 was not detected in our experimental conditions. Conclusions: Our study showed that reduction of liver injury by PGE 1 or anti-TNF-...
for NIK in hepatocyte apoptosis in a mouse model of virus-induced TNFR1/RIP1-dependent liver damage. We conclude that NIK not only contributes to lymphoid organogenesis, inflammation and cell survival but also to TNFR1/RIP1-dependent cell death independently of the alternative NF-κB pathway....
Accordingly, it is possible that the activation of TNF-a/TNFR1 signaling in the tumor microenvironment promotes gastric tumor development through induction of Noxo1 and Gna14, which contribute to maintaining the tumor cells in an undifferentiated state. The present results indicate that targeting the...
role for NIK in hepatocyte apoptosis in a mouse model of virus-induced TNFR1/RIP1-dependent liver damage. We conclude that NIK not only contributes to lymphoid organogenesis, inflammation and cell survival but also to TNFR1/RIP1-dependent cell death independently of the alternative NF-κB ...