Human CD40 LigandCD40 Ligand, also known as TNFSF, CD154, TRAP, and gp39, is a 34-39 kDa type II transmembrane glycoprotein that belongs to the TNF superfamily (1-3). Mature human CD40 Ligand consists of a 22 amino acid (aa) cytoplasmic domain, a transmembrane segment, and an...
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identified. MR identified ALB, TNF, PPARα, and PPARγ as key targets. Molecular docking indicated that baicalin, naringenin, and curcumin exhibited suitable binding activities to these targets, further confirming by LC-MS analysis. The IC50of TTF in HCAECs was 18.25 mg/mL. TTF treatment s...
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英文别名: C1QTNF4 Antibody - middle region (ARP52425_P050)中文名: 中文别名: CBNumber: CB115435487 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 C1QTNF4 Antibody - middle region (ARP52425_P050)化学性质 安全信息...
使用特异性抑制剂和si RNA转染研究了信号转导和转录激活因子3(Stat3)信号通路在自噬过程中的作用.结果 TNF-α诱导OCCM-30细胞自噬,经TNF-α处理后,Atg-5和Beclin-1的表达增加并表现出时间依赖性和浓度依赖性.Stat3信号通路被TNF-α激活,并且Stat3信号通路被抑制后自噬相关蛋白的表达下调.结论本研究提示TNF-α能够...
To elucidate whether pancreatic acinar cell submitted to stress is able to express TNF-α, we studied TNF-α mRNA expression by Northern blot and in situ hybridization in healthy pancreas, in tissue from caerulein-induced pancreatitis and after lipopolysaccharide (LPS) treatment. In specimens from...
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2型糖尿病并发冠心病患者血清脂联素、TNF-α和hs-CRP检测的临床意义