Further, in silico modeling was done to predict secondary structure of mRNA for g.鈥鈥T鈥gt;鈥塆 polymorphism in the ADIPOQ gene by RNA fold. Results: The minor allele frequency observed in the controls for the TNF-伪 G鈥gt;鈥堿 and ADIPOQ T鈥gt;鈥塆 polymorphisms were 0.07 and 0.10,...
Our results demonstrated that IL-27 induced and synergized with TNF-伪 to up-regulate CXCL10 mRNA and protein concentrations in a steroid-insensitive manner. This synergistic CXCL10 production was dependent on the transcriptional regulation of CXCL10 gene promoter activity and the enhanced stability ...
J. In situ mRNA hybridization technique for analysis of metastasis-related genes in human colon carcinoma cells. Am. J. Pathol., 147: 1238 -1247, 1995.Albaugh, G., Kann, B., Strande, L., Vemulapalli, P., Hewitt, C., and Alex- ander, J. B. (2001). Nicotine induces endothelial ...
Elevated levels of TNF-伪 associated with RBM10 overexpression resulted from increased TNF-伪 transcription, not TNF-伪 mRNA stabilization. These results suggest that RBM10 has the ability to mo...
ChIP and Luciferase assays show that TNF-α inhibits CRE to inhibit SNAT2 mRNA transcription.When taken together along with Kinetics, Western blotting, immunocytochemistry, and qRT-PCR demonstrated that TNF-α transcriptionally inhibits SNAT2 via CRE in IEC-6 cells. Thus, this study provides new ...
We found that SalB, as well as NADPH oxidase inhibitors, DPI or apocynin, and antioxidant NAC, inhibited TNF-伪-induced MMP-2 mRNA, protein expression, and gelatinolytic activity in HASMCs in a concentration-dependent manner. We also observed a dose-dependent decrease in ROS production and ...
Post-burn hypertrophic scars are characterized by high levels of IL-1尾 mRNA and protein and TNF-伪 type I receptorsSalgadoRosa MC. AdrianaMarcoChristianMercadilloPatriciaMorenoLuis M
Moreover, T0901317, a LXR agonist, significantly increased the ABCG1mRNA expression by 3 times when 5?μg/ml T0901317 treated HUVECs for 24?h. With upregulation of ABCG1, decreased NOS activity induced by TNF-α was reversed about 47%, and concomitant NO levels was reversed by 30% ...