两个受体膜内部分最主要的区别在于TNFR1上面有一个死亡区域，TNFR2上没有，这一死亡区域是一段约70个氨基酸的序列，这一区域对TNF-α启动的细胞凋亡是必须的。与Fas蛋白的死亡区域相似，这一细胞内的区域是种附属信号蛋白的结合位点，这些蛋白包括Fas相关死亡区段结合蛋白（FADD），TNFR-1相关死亡区段...
Tumor Necrosis Factor-Beta Human Recombinant CYT-224 5µg ($60) 20µg ($145) 1mg ($2700) Shipped at Room temp. TNF b Human, His More Info Tumor Necrosis Factor-Beta Human Recombinant, His Tag CYT-495 5µg ($60) 20µg ($145) 1mg ($3600) Shipped with Ice Pac...
TNF-beta /LT-alpha is expressed in activated T- and B-lymphocytes. In addition to its cytotoxic action on tumor cells, TNF-beta /LT-alpha has been shown to be a mediator of inflammation and immune function. Evidence is also accumulating that TNF-beta /LT-alpha and TNF-alpha are mediators...
TNF-alpha蛋白鼠源是一种重要的生物试剂,主要用于科研领域。瑾萱生物生产的Mouse IFNbeta重组蛋白,有效成分含量高达100%,非进口产品。该蛋白仅供科研使用,适用于多种研发项目。蛋白的种属是Mouse,表达宿主为HEK293cells,具有C-hFcHis标签。此外,它的纯度大于95%,内毒素小于1EU/μg。该重组蛋白以PBS缓冲液作为制剂,...
JTE-607 inhibits tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-6, IL-8 and IL-10, from LPS-stimulated human PBMCs, with IC50 values of 11 nM, 5.9 nM, 8.8 nM, 7.3 nM and 9.1 nM, respectively. S3231 UCB-9260 UCB-9260 is an orally active inhibitor that inhibits ...
TNF-alpha and IL-1beta increase Ca2+ leak from the sarcoplasmic reticulum and susceptibility to arrhythmia in rat ventricular myocytes. TNF-alpha and IL-1beta increase Ca2+ leak from the sarcoplasmic reticulum and susceptibility to arrhythmia in rat ventricular myocytes . Cell Calcium . ... DJ ...
tumour necrosis factor-alpha (redirected fromTNF-alpha) TNF A gene on chromosome 6p21.3 that encodes a cytokine, primarily secreted by macrophages, which binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF can induce cell death of certain tumour cell lines, and it is a potent pyrogen causing...
Purified anti-human LT-α (TNF-β) Antibody - Lymphotoxin-α (LT-α), also known as tumor necrosis factor-beta (TNF-β), is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other tar
but shows a single 17 kDa band following SDS PAGE under non reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumour Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis or cytostasis of certain transformed cells,...
Simple Plex 16x4 panel containing IL-1 beta / IL-1F2, IL-6 3rd Gen, IL-8/CXCL8, and TNF-alpha 2nd Gen with sample diluent SD13. Part # starting with ST01 ships in 3-5 days. Sample type indicated with PS (Plasma/Serum). Non-Human Primate TNF-a Cartridge Catalog #: SPCKB-NP...