Association of TNF-alpha and TNFR1 promoters and 30 UTR region of TNFR2 gene polymorphisms with genetic susceptibility to tabacco-related oral carcinoma in Asian Indians[J].Oral Oncology,2008,(05):455-463.doi:10.1016/j.oraloncology.2007.06.003....
产品活性:肿瘤坏死因子 α (TNF alpha) 是一种有效的促炎细胞因子。TNF alpha 与其受体结合,主要是 TNFR1 和 TNFR2,然后传递信号以实现炎症和细胞死亡等生物学功能。TNF alpha 通过 TNFR2 受体激活 NF-κB 通路促进癌细胞生长、侵袭和转移,但抗 TNF-α 抗体能显着抑制结肠炎相关癌症 (CAC) 小鼠的肿瘤发展。
产品活性:肿瘤坏死因子 α (TNF alpha) 是一种有效的促炎细胞因子。TNF alpha 与其受体结合,主要是 TNFR1 和 TNFR2,然后传递信号以实现炎症和细胞死亡等生物学功能。TNF alpha 通过 TNFR2 受体激活 NF-κB 通路促进癌细胞生长、侵袭和转移,但抗 TNF-α 抗体能显着抑制结肠炎相关癌症 (CAC) 小鼠的肿瘤发展。
上海玉博生物科技有限公司做为cisbio代理商之产品64BDTNFPEG-Human TNFalpha/TNFR1 binding kit的产品销售公司,专业经营原装进口抗体(单克隆、多克隆)、重组蛋白、检测试剂盒、标准品、细胞因子、胎牛血清、细胞培养类等生物试剂以及耗材。 玉博生物致力于成为科研试剂采购一体化解决方案提供商! 1,货品多且全,目前,...
Superoxide anion-induced pain and inflammation depends on TNF alpha/TNFR1 signaling in mice 来自 国家科技图书文献中心 喜欢 0 阅读量: 18 作者:Yamacita-Borin,Fabiane,Y.,Alves-Filho,Jose,C.,Cunha,Thiago,M.,Fattori 摘要: Inhibition of tumor necrosis factor-alpha (TNF alp 关键词:...
PGE 1 or antiTNF± was administered at 30 or 60 min before DGalN, respectively. Liver injury was evaluated by alanine aminotransferase (ALT) activity in serum and histological examination in liver sections. TNF±was determined by ELISA in serum. The expression of TNF± receptor type 1 (TNFR1...
All hearts with low over-expression of TNFα, independent of human or murine origin, have improved contractile performance and increased Ca 2+ sensitivity (by 0.2–0.26 pCa). Hearts lacking TNFR1 have contractile performance equal to wild type hearts. Recovery from ischemia was greater in TIA-1...
involving the execution phase of apoptosis and inhibition of TNFR1/IKB alpha/p65 signaling. Therefore, small molecules such as PNU-74654 may identify potential new treatment strategies for TC. Keywords: PNU-74654;TNF receptor-1;apoptosis;testicular cancer...
[Side-effects of anti-TNF alpha agents]. Background. Pityriasis lichenoides is a rare cutaneous disorder of unknown origin that mainly affects children and young people. The disease consists of tw... JL Schmutz,A Barbaud,P Trechot - 《Annales De Dermatologie Et De Vénéréologie》 被引量...
产品活性:肿瘤坏死因子 α (TNF alpha) 是一种有效的促炎细胞因子。TNF alpha 与其受体结合,主要是 TNFR1 和 TNFR2,然后传递信号以实现炎症和细胞死亡等生物学功能。TNF alpha 通过 TNFR2 受体激活 NF-κB 通路促进癌细胞生长、侵袭和转移,但抗 TNF-α 抗体能显着抑制结肠炎相关癌症 (CAC) 小鼠的肿瘤发展。