Finally, when we just about couldn’t take any more of the waiting, a candidate arrived in the form of Phil Falcone(y), a former aide to Mayor Patricia Lock-Dawson, who from what we can tell is about the least oppressed person in Riverside according the Intersectionality Olympics competitio...
zebrafish andC. eleganshave shed light on the proteins that form the MT complex and their probable roles in its function2. These include the tip link proteins, protocadherin-15 and cadherin-23, which in hair cells transduce the force derived from stereocilia displacement to the opening of ...
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Release of Ca2+from intracellular stores is facilitated by a series of ion channels in the ER. However, little is known about how intracellular Ca2+signaling is regulated by these channels during osteoblast differentiation. Transmembrane and coiled-coil domain 1 (TMCO1) have been reported to be a...
Since the discovery of TMEM16A (anoctamin 1, ANO1) as Ca2+-activated Cl− channel, the protein was found to serve different physiological functions, d
Download: Download full-size image Figure 3. Analysis of Transducer Adaptation in Tmc Mutant Hair Cells Recorded in 50 μM Ca2+ (A–C) Whole-cell mechanotransduction currents (left) recorded from inner hair cells of Tmc1Δ/Δ;Tmc2+/Δ (n = 14 cells), Tmc1+/Δ;Tmc2Δ/Δ (n = 16...
Download: Download full-size image Figure 3. Analysis of Transducer Adaptation in Tmc Mutant Hair Cells Recorded in 50 μM Ca2+ (A–C) Whole-cell mechanotransduction currents (left) recorded from inner hair cells of Tmc1Δ/Δ;Tmc2+/Δ (n = 14 cells), Tmc1+/Δ;Tmc2Δ/Δ (n = 16...
Lifting speed (full load / no load) 250/350mm/s 230/350mm/s Descent speed (full load / no load) 600/300mm/s 600/300mm/s Maximum grade climbing capacity 15° 16° Service brake type Hydraulic pressure Hydraulic pressure Parking brake type Mechanics Mechanics...
C. elegans is a free-living bacterivore containing B1,000 somatic cells, 60 of which form the pharynx and its associated neurons. The pharyngeal system pumps in, grinds up and transfers bacterial food into the intestine4. The laboratory diet for C. elegans is E. coli OP50. At 20 °C,...
age P6, followed by microdissection of the organ of Corti. Freshly prepared FM1-43 was added to the culture for 10 s and then washed twice (5 min each wash) with minimum essential media. Live tissues were imaged with a 40× water immersion objective in an LSM 800 (Carl Zeiss) ...