Here, we present the real-world prevalence of TMB-High in a large cohort of gynecologic tumors and examine its correlation to other ICPI biomarkers. Methods: We retrospectively reviewed 17,304 gynecologic tumors tested with comprehensive genomic profiling (CGP). TMB was determined on 0.79 Mb of ...
环绕着勃朗峰有一条传统的徒步旅行路线叫TMB(tour du mont blanc)徒步者会根据自身情况用6-7天来这条世界级徒步线路,UTMB的赛道就是脱胎于TMB环勃朗峰步道,UTMB(The Ultra-Traildu Mont-Blanc)就是在环勃朗峰的路线上举行的越野赛。 UTMB—在天际与高海拔的群山间肆意追逐,精彩绝伦的赛道赛道为越野跑的根基,也...
“KEYNOTE-158 has confirmed clinical activity of pembrolizumab in tumors harboring a TMB ≥10 (TMB-High) across a variety of previously treated solid tumors including anal, biliary, cervical, endometrial, mesothelioma, neuroendocrine, salivary, small cell lung, thyroid, and vulvar cancers. A respons...
例如,在KN-158研究中,TMB-H组与非TMB-H组的中位PFS都是2.1个月,且TMB-H组的中位OS短于非TMB-H组的中位OS(11.7个月 vs 12.8个月),tTMB-H组患者生存获益更差? 这确实是TMB当前面临的一个问题,对于tTMB-H患者生存获益不显著这一点,主要的原因是KN-158的泛瘤种研究中纳入了大量常表现为tTMB-H状态,...
产品名称:TMB, High Kinetics 产品型号: 产品展商:其它品牌 产品文档:无相关文档 简单介绍 CAS:54827-17-7Formula:C16H20N2MW:240.35Appearance:LiquidPurity:N/A TMB, High Kinetics的详细介绍 3,3',5,5'-Tetramethylbenzidine (TMB) has been shown to be a safe, sensitive substrate for the assay of ho...
百度试题 结果1 题目研究表明,以下符合胆囊癌免疫治疗的指标是( ) A. TMB-Low B. MSI-High C. CEA-Low D. AFP-High 相关知识点: 试题来源: 解析 B 反馈 收藏
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TMB沉淀(高灵敏度),TMB Precipitating (High Sensitivity) 其他 ScyTek公司始建于1991年,以成为世界级生命科学研究试剂生产商为目标。ScyTek从创立之初就采取了严格的原材料筛选程序,生产多种优质试剂,不断应用于各种学科,包括免疫学,组织学,细胞学,微生物学和血液学等。ScyTek公司的ELISA试剂包括显色底物,结合物稳定...
CheckMate-026研究的描述,以下说法正确的是?A.主要研究终点PFS和OS并没有达到统计学意义B.主要研究终点PFS和OS达到了统计学意义C.事后分析发现,TMBhigh的人群PFS达到了统计学意义D.事后分析发现,TMBhigh的人群PFS未达到统计学意义
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