NZ suppresses TLR4/NF-kappaB signalings and NLRP3 inflammasome activation in LPS-induced RAW264.7 macrophages. Inflammation research: official journal of the European Histamine Research Society. 64, 799-808 (2015).P. Xiang, T. Chen, Y. Mou et al., "NZ suppresses TLR4/NF- 𝜅B signalings ...
Knockdown of hsa_circ_0068087 suppressed HG-induced HUVEC dysfunction and inflammation by suppression of the TLR4/NF-kappa B/NLRP3 inflammasome signaling pathway. Downregulation of miR-197 reversed hsa_circ_0068087 silence-induced HUVEC dysfunction and inflammation in the HG condition. It was found ...
Monocytes from 20 preeclamptic and 20 normotensive (NT) pregnant women, and THP-1 cells were cultured with/without hyaluronan (HA), PG, or VD to determine gene and protein expression of TLR4 receptor, phosphorylated NF-kappa B, I kappa B alpha, TLR4, MYD88, NF-kappa B, NLRP1, NLRP3...
TLR4NLRP3PyroptosisBackground and aim: The Toll-like receptor 4 (TLR4)/nuclear factor kappa B (NF-kappa B)/NLRP3 inflammasome signaling pathway is essential in the pathogenesis of hepatic ischemia/ reperfusion (HIR) injury. Pyroptosis is a pminflammatory programmed cell death that is related to...
The involved underlying mechanisms of harmine in LPS-induced acute kidney injury might be related to inhibition of the TLR4-NF-kappa B pathway and NLRP3 inflammasome pathway. Based on the above conclusion, it is possible for harmine to be used to clinically treat acute kidney injury....
Renshen Shouwu extract enhances neurogenesis and angiogenesis via inhibition of TLR4/NF-kappa B/NLRP3 signaling pathway following ischemic stroke in ratsRenshen shouwu extract (RSSW)Ischemic strokeNeurogenesisAngiogenesisNLPR3Ethnopharmacological relevance: Renshen Shouwu extract (RSSW) is a patented ...
Atorvastatin suppresses NLRP3 inflammasome activation via TLR4/MyD88/NF-κB signaling in PMA-stimulated THP-1 monocytes. Biomed Pharmacother 2016; 82: 167-172.Atorvastatin suppresses NLRP3 inflammasome activation via TLR4/My D88/NFkappa B signaling in PMA-stimulated THP-1 monocytes. KONG F,YE B,...