TAK-242是一种有效的TLR4抑制剂,选择性抑制TLR4调节的细胞因子和NO产生。注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!CAS号:243984-11-4别名:Resatorvid纯度:99.95%分子式:C15H17ClFNO4S分子量:361.82结构式:储存条件:-20℃,有效期2年,溶入溶剂后-20℃请尽量在一个月内使用。相关搜索:TLR4抑制剂(...
产品名称:TLR4 Inhibitor, TAK-242 .0订购此产品 供应商:Merck 规格:PC 目录价:2067 库存状态:3周到货 CAS编号:243984-11-4 应用范围:生化实验 种属来源: 相关信息: TLR4 Inhibitor, TAK-242 Ethyl-(6R)-6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate ...
探讨Toll样受体4(TLR4)特异性抑制剂TAK-242对人多发性骨髓瘤细胞株 RPMI8226增殖和凋亡的影响,以及其可能的作用机制。 方法 取对数期生长的人多发性骨髓瘤细胞株RPMI8226,分为A组、B组、C组 以及对照(CON)组,A组、B组、C组分别加入终浓度为20、40、80μmol/L ...
In this study, we examined the anticancer effects of TAK2, a small molecule inhibitor of TLR4, on different breast cancer cell lines: MCF7, SKBR3, MDA㎝B1, and BT4. Our results showed that the TLR4 inhibition, as revealed by the downregulation of TLR4 downstream genes, exerted desirable ...
Yuko Ono, et al. TAK-242, a Specific Inhibitor of Toll-like Receptor 4 Signalling, Prevents Endotoxemia-Induced Skeletal Muscle Wasting in Mice. Sci Rep. 2020 Jan 20;10(1):694. HB221205
Jalan教授课题组在Journal of Hepatology(IF: 30.0)杂志上发表题为“Combination of G-CSF and a TLR4 inhibitor reduce inflammation and promote regeneration in a mouse model of ACLF”的文章[1]。TLR4抑制TAK-242可挽救G-CSF驱...
Then the same assays, in addition to anoikis resistance, cell cycle and annexin V/PI apoptosis tests, were used to investigate whether the inhibition of TLR4 using a small molecule inhibitor, TAK-242, could suppress the proliferation of various OC cell lines: A2780CP, 2008C13, SKOV3, and ...
InSolution TLR4 Inhibitor, TAK-242会员价请登录市场价￥1097原厂型号 5.08336.0001 贝雷猫货号 RH156196 品牌 默克密理博/Millipore 单件重量 1kg 货期 45天 单位: 盒 包装: 盒 库存: 0 数量: 盒 + - 1盒起订,增量1盒 加入购物车立即购买 ...
Lipopolysaccharide (LPS) and TLR4 inhibitor (TAK-242) were used to further verify the mechanism of harpagoside. The co- 收稿日期:2023-01-03 基金项目:国家重点研发计划项目(2022YFC3501403);江苏省自然科学基金资助项目(BK20191506);深圳市"医疗卫生三名工程"项目 (SZZYSM202111011) 作者简介:郝任娟(...
Furthermore, the TLR4-specific inhibitor TAK-242, a cell-permeable cyclohexenecarboxylate interacting with the adaptor molecules TIRAP and TRAM via directly binding to the intracellular Cys747 residue of TLR428,29, was used to block the TLR4 signalling pathway. RAW264.7 cells were subsequently ...