Jian WangofLei XueThoracicHailong CaoandFei CuiCardiovascularTing DaiSurgeryYijiang Chenthe生物医学研究杂志(英文版)Wang J, Xue L, Cao H, Cui F, Dai T, Chen Y. TLR2 was over- expressed independent of IL-6 in patients with valvular atrial fibrillation. J Biomed Res 2011; 25: 178-84....
TLR2 induced IgA glycosylation via APRIL/IL-6 pathways in IgA nephropathy 引用 收藏 分享 摘要 [目的]探讨Toll样受体2(TLR2)通过增殖诱导配体(APRIL)/白细胞介素-6(IL-6)介导免疫球蛋白A(IgA)糖基化对IgA肾病的影响。[方法]将8周龄SD雄性大鼠通过诱导方式,以含0.1%浓度牛的血清白蛋...展开更多 [...
摘要: 通过观察TLR2蛋白阻断前后HCV阳性血清处理BV-2细胞培养上清液中MCP-1、IL-6及IL-12的表达,为进一步探讨HCV引起中枢神经系统免疫反应特点奠定基础.细胞分为空白对照组(常规培养用DMEM高糖培养液)、正常对照组(含有20%正常血清的DMEM高糖培养液)、实验组(含有20% HCV阳性血清的DMEM高糖培养夜),每组分为4h、8...
结论:TLR2、TLR4与血清TNF-α、IL-6可能共同参与COPD的发展,稳定期COPD患者TLR2、TLR4表达明显下降,可以通过调整TLRs水平来控制急性期COPD体内患者的炎症症状。 【关键词】慢性阻塞性肺病;TLR2;TLR4;TNF-α;IL-6 【中图分类号】R563【文献标识码】A【文章编号】2095-1752(2017)17-0148-01 细胞因子在慢性阻塞...
5.造模后,提取自TLR2缺陷鼠的肠上皮培养上清中IL-6的浓度较野生鼠的低。结论:在实验性肠炎模型中,巨噬细胞和肠上皮细胞上TLR2的缺失可以减少IL-6和IL-23的分泌进而减少IL-17~+T细胞的分化来缓解肠炎。 展开 关键词: TLR2 IL-17 巨噬细胞 肠上皮细胞 ...
16, Pages 159-177: Upregulation of TLRs and IL-6 as a Marker in Human Colorectal Cancer Toll-like receptors (TLRs) not only form an important part of the innate immune system but also serve to activate the adaptive immune system in response to cancer. Real-time PCR; immunohistochemical ...
The study was undertaken to investigate the interrelation of toll-like receptor (TLR) and interleukin (IL)-17 in the salivary glands of patients with primary Sjogren's syndrome (pSS) and to determine the role of TLR and IL-17 in the pathophysiology of pS
The expressions of various TLRs, IL-17 and the cytokines involved in Th17 cell differentiation including IL-6, IL-23, tumor necrosis factor-alpha (TNF-α) and IL-1β were examined by immunohistochemistry in salivary glands of pSS patients. The IL-17 prod
LPS）的作用；而加入TLR2抗体后，SNP组巨噬细胞RAW264.7的上述各细胞因子的分泌量相较未加TLR2抗体组均降低，但除IL-6细胞因子外差异均不显著。由此可见，SNP可促进巨噬细胞RAW264.7的增殖及细胞因子的分泌，但不是通过TLR2受体介导。关键词：广叶绣球菌中性多糖；巨噬细胞RAW264.7；高效凝胶渗透色谱法；细胞...
2006. Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production. J. Immunol. 176: 3635-3641.Horwood N, Page TH, McDaid JP, Palmer CD, Campbell J, Mahon T et al. Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL...