产品活性:TAB1 蛋白是响应 TLR 和细胞因子刺激而激活 JNK、NF-kappa-B 和促炎细胞因子的关键接头。它与 MAP3K7/TAK1 结合,诱导自身磷酸化和完全激活。TAB1 蛋白, Human 是重组的 TAB1 蛋白,由 E. coli 表达,不带标签。TAB1 蛋白, Human 全长 370 个氨基酸。 研究背景:TAB1
Aged garlic extract preserves beta-cell functioning via modulation of nuclear factor kappa-B (NF-κB)/Toll-like receptor (TLR)-4 and sarco endoplasmic reticulum calcium ATPase (SERCA)/Ca2+ in diabetes mellitus Sofi Imtiyaz Ali, Ahmed M. E. Elkhalifa, Showkat Ul Nabi, Faisal Sualeh Hayya...
2.8. EVsderived from M. pneumoniae-Infected Macrophages Stimulate the Production of Inflammation Cytokine by Activating NF-κB and MAPK Pathways NF-κB (p65, RelB, c-Rel, NF-κB1, and NF-κB2) and MAPK (ERK, p38, and JNK) signaling pathways, as the downstream signals of TLR2 are essen...