Telethonin (Titin Cap Protein, TCAP, T-cap) 供应商 MyBioSource 产品货号 MBS641309 产品报价 ¥询价/0.1mg ¥询价/5x0.1mg ¥询价/其它规格 产品说明书 点击查看 购买方式 MyBioSource中国区金牌代理,部分产品现货库存。银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868 ...
Titin, encoded byTTN, is the largest known protein and is expressed in cardiac and skeletal muscles. Spanning the Z-disk to the M-band, it is involved in sarcomeric assembly and function3. Expression and processing ofTTNis age- and tissue-specific and involves complex transcriptional regulation4...
For the identification of protein complexes, the protocol from Roux et al.16 was modified. Fifty milligrams of cryo-fractured tissue powder was resuspended with 0.5 ml BioID lysis buffer (50 mM Tris pH 7.5; 500 mM NaCl; 0.4% SDS; 5 mM EDTA; 1 mM DTT; 2% Triton X and ...
Phosphoregulation of the Titin-cap Protein Telethonin in Cardiac Myocytesdoi:10.1074/jbc.M113.479030Alexandra J CandasamyRobert S HaworthFriederike CuelloMetin Avkiran
(Li-COR Biosciences). The primary antibodies that were used for western blotting, superresolution SIM, and IEM are shown in Supplementary Table3. Uncropped western blot images using Z1Z2 antibody (Supplementary Fig.7) and M8-9 antibody (Supplementary Fig.8) are provided. For MHC protein ...
Perrot A, Posch MG, Osterziel KJ (2006) Deletion of Glu at codon 13 in the TCAP gene encoding the Z-disc protein titin-cap/telethonin is a rare non-synonymous polymorphism. Mol Genet Metab 88:199–200. : 10.1016/j.ymgme.2006.01.004...
protein domains, some uncertainty exists with respect to the exact binding site(s) of the antibody. Assuming that they are in the middle of the protein fragment (for both A40-A41 and A165) results in 124.5 domains contained with the segment, and an average domain spacing of 3.99 nm. ...
At its amino terminus near the Z-line, repeats Z1-Z2 interact with telethonin (T-cap), which in turn interacts with a potassium channel subunit, myostatin, a muscle growth factor (17), and the muscle LIM protein, MLP (18). Z-line repeat Z4 and the 700-kDa titin isoform “novex-...