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imdevimab (REGN-COV), a cocktail of neutralizing antibodies against the receptor-binding domain of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, was shown to be an effective treatment and post-exposure prophylaxis measure for coronavirus disease 2019 (C...
One of the limited number of choices for the treatment of coronavirus disease 2019 (COVID-19) is to administer plasma, containing neutralizing anti-viral antibodies, from donors who have recovered from the disease. This so-called convalescent plasma (CP) is a form of passive immunotherapy that ...
investigators are seeking more automated analytical solutions for assessment of viral vector identity, purity, and stability. Simple Plex AAV assays on the Ella platform provide an accurate and efficient method for measuring the AAV capsid titer. The assay uses the recombinant AAV antibodies from indus...
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Age, comorbidity, smoking, alcohol, and exercise habit significantly correlate with the increase of the participants' antibodies (P < 0.001). The age shows that the younger the participant, the higher the titer antibody 2 will be (P = 0.001, 95% confidence interval [CI],-1.935,-0.694). ...
COVID-19 serotherapySARS-CoV-2Severity of illness indexAntibodiesThe use of COVID-19 convalescent plasma (CCP) has been approved by the FDA. We assessed the outcome of patients with moderate and severe COVID-19 following convalescent plasma therapy and the association with variables such as ...
COVID-19Disease severitySARS-CoV-2Background:It remains unclear whether high titers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies aggravate clinical manifestations in patients or whether severe clinical manifestations result in high antibody titers. Thus, we investigated the...
The efficacy of using viral vector vaccine boosters is questionable since viral vector COVID-19 boosters fail to generate enough antibodies to achieve the mean convalescent plasma level.#Higher antibody levels than the typical convalescent level and that needed for half protective property are still ...
antibodiesCOVID‐19immunityvaccinationThis study (1) determined the association of time since initial vaccine regimen, booster dose receipt, and COVID‐19 history with antibody titer, as well as change in titer levels over a defined period, and (2) determined risk of COVID‐19 associated with ...