In addition, Ki-67 was one of the representative marker of proliferative potential of osteosarcomas [42]. Moreover, the expression of Ki-67, a representative marker of proliferative potential of osteosarcomas in tumor tissues were assessed (Fig. 4G). The results indicated that the expression ...
Additionally, tumours in the craniomaxillofacial region, whether benign or malignant tumours may cause localised tissue abnormalities. Ameloblastoma is a common benign disease that originates from odontogenic epithelial cells and results in the formation of a severe intraosseous mass that exhibits aggressi...
copper oxide, zinc oxide, and manganese oxide) [33,34]. The long-term stability of TiO2nanomaterials in biological conditions is another advantage that can protect the loaded biomolecules from denaturation in comparison to other unstable (degradable) nanomaterials in an aqueous solution (i.e., a ...
inflicted by the intratracheally instilled TiO2, clearly depended upon the diameter of its particles. Kobayashi et al. [63] reported the pulmonary toxicity of TiO2NPs in rats, evaluated on the basis of the short-term post-installation lung injury (up to 7 days after the installation...
Morphological data by 4′,6-diamidino-2-phenylindole (DAPI) staining showed nuclear fragmentation, which is a marker of apoptosis. Western blot analysis of TiO2-NP-treated cells showed that expression of cytochrome c was activated, suggesting the trigger of apoptosis via mitochondria-mediated pathway...
Heterogeneous nuclear ribonucleoproteins regulate the surface receptor glycoprotein CD4444 that acts via a range of signaling kinases, but especially Ras-MAPK pathways, terminating in gene transcription at the nucleus. We thus used western blot techniques to quantify the marker ERK1/2 protein of the ...
As such, titanium dioxide-based nanocomposite upon photoactivation has a good potential as a photosensitizer in PDT for breast cancer treatment. Keywords: titanium dioxide; N-doped graphene quantum dots; photodynamic therapy; near-infrared light; reactive oxygen species; apoptosis Graphical Abstract...
The following antibodies were used for marker detection: For Ki67; Clone MIB-1 (Code M7240 Dako Denmark A/S Produktionsvej 42 DK-2600, Glostrup, Denmark); for TUNEL (S7101; Millipore, Billerica, MA, USA) was used. After DAB staining cell nuclei were counterstained with hematoxylin and ...