Bottom-up synthesis of prototissues helps us to understand the internal cellular communications in the natural tissues and their functions, as well as to improve or repair the damaged tissues. The existed prototissues are rarely used to improve the funct
Fig. 1: Characteristics of samples in the pilot phase of PigGTEx project. a, Clustering of 7,095 RNA-seq samples based on the normalized expression (log10-transformed TPM) of 6,500 highly variable genes, defined as the top 20% of genes with the largest s.d. of TPM across samples. b...
IHC staining was performed as previously described [28] on 4 µm sections of FFPE tissue samples with 3,3’-diaminobenzidine as the chromagen, using a Leica BOND Rx auto-stainer (Leica, Nussloch, Germany) using pre-defined protocols. DNA sequencing DNA was extracted from FFPE tissue samples...
The x dimension is defined as x = 2πψ. The center of the stem cell pool is placed such that the origin of the center of this circular stem cell pool whose size, and thus number of stem cells allowed within this pool, is placed at (h,k) where h = x/2 and k =...
Based on the size, PMs can be defined as coarse particles (PM10,<10 µm in aerodynamic diameter), fine particles (PM2.5,<2.5 µm in aerodynamic diameter), and UFPs (<100 nm in aerodynamic diameter) [6]. Among them, UFPs are thought to be the most concern in inducing detrimental ...
Furthermore, as shown in the “Results” section below, only a comprehensive analysis allows comparison across these classes. Complete details of ROP, including all parameters and thresholds used, are provided in the Additional file 1: Supplementary Methods....
As an organism is made up of many different tissues and organs, each with its own genetic programme, it is pertinent to ask: How relevant is tissue in terms of total transcriptome variability? Which are the genes most distinctly expressed between tissues? Does breed or sex equally affect the...
Syndrome (SARS) and the Middle East respiratory syndrome (MERS). To date, COVID-19 has caused over 5 million deaths worldwide [1,2]. Due to the emergence of this infection, researchers are striving to understand the mechanisms of the infection, the best treatment options, and vaccine ...
The current classification employs indicators such as vessel diameter, distance between vessels, and cross-section shape. All of these indicators are statistically significant and allow for the quantitative analyses of various aspects of wood structure [2,5]. For most species, the repeatability and ...
The SILAC ratio of one protein was defined as the relative intensity ratio of Leu-d0-containing peptides from each kind of tissues versus that of Leu-d3-labeling peptides from H4 cells, and it was averaged when several peptides were used for quantification for one protein. The SILAC ratio...