Cellular calcium (Ca) exchange in arterially perfused whole heart is markedly perfusion-limited. Therefore, a large fraction of exchangeable Ca recycles within the cell before exchanging with extracellular Ca. Ca enters the cell via sarcolemmal (SL) transient (T) and long-lasting (L) channels act...
Because ADPSBQ and ADPVSC have more distinct roles in the body23, we sought to better understand what drove differential gene expression based on sexual dimorphism. We clustered co-correlating matrisome genes within ADPSBQ, generating 3 gene clusters. One cluster separated into two negatively ...
Macrophages are tissue-resident immune cells that act as important immune sentinels and concomitantly execute vital homeostatic tasks to ensure tissue integrity and functionality. Indeed, macrophages are present in virtually every organ of the body. They colonize tissues to form self-maintaining populations...
In tissue engineering, the term of cardiovascular involves the creation of the cardiac system and vascular tissues, for instance, the blood vessels, myocardium and heart valves. Show moreView chapterExplore book Biodegradable polymer matrix nanocomposites for bone tissue engineering Mohammad S. Hasnain,...
The reservoir can be used to administer stem cell therapies, acting as a cell factory. Rather than pass through the membrane into the heart, the stem cells stay within the reservoir where they produce paracrine factors that promote healing in the damaged heart tissue. ...
Deep tissue bio-imaging using two-photon excited CdTe fluorescent quantum dots working within the biological window. These penetration depths have been used to obtain the first deep tissue multiphoton excited fluorescence image based on CdTe-QDs. Due to the large thermal... L M,Maestro,J E,.....
Approximately 25–70 % of subjects develop prediabetes to T2DM within 3–5 years in their lifetime, and 80 % of them develop the non-alcoholic fatty liver disease [15,16]. Insulin resistance also increases the risk of heart failure, fuels tumor growth, and declines memory functions that ...
The recapitulation of previous arrangements of cell types during regrowth. Patterning The developmental process by which cells acquire their identities, depending on their relative spatial positions within the embryo. Ontogenetic Relating to the developmental history of an organism from fertilization to adult...
Specifically, a 4:1 AA:PU weight ratio in the precursor solution was found to produce materials within the upper limit of final PAA content (Supplementary Fig. 5). Prior to 3D printing, the PAA-PU solutions may be blended with PU to further tune the PU content of the ink as desired. ...
State of the art and future directions of scaffold-based bone engineering from a biomaterials perspective. J Tissue Eng Regen Med. 2007;1:245–60. Article CAS PubMed Google Scholar Murphy WL, Kohn DH, Mooney DJ. Growth of continuous bonelike mineral within porous poly(lactide-co-glycolide)...