Nowadays, obesity is seriously increasing in most of the populations all over the world, and is associated with the development and progression of high-mortality diseases such as type-2 diabetes mellitus (T2DM) and its subsequent cardiovascular pathologi
Perivascular adipose tissue (PVAT) is a highly metabolically active tissue which surrounds the majority of blood vessels and contributes to the modulation of vascular tone [1,2,3]. Previously, we have presented evidence that the mechanisms of this effect are mediated via the sympathetic nervous sy...
In health, PVAT secretes anti-contractile factors that relax the underlying artery. PVAT’s contributions to vascular function include more than production of vasoactive substances. We hypothesized that PVAT benefits the artery by assisting the function of stress (–induced) relaxation. Thoracic aorta...
Conventional surgical treatment for cardiovascular diseases such as cardiomyopathy using left ventricular assist device (LVAD) or heart transplantation often have some additional drawbacks after the operation because of limited durability in the long term1,2,3. Using tissue engineering approaches, the ...
Conventional surgical treatment for cardiovascular diseases such as cardiomyopathy using left ventricular assist device (LVAD) or heart transplantation often have some additional drawbacks after the operation because of limited durability in the long term1,2,3. Using tissue engineering approaches, the ...
Soft tissue including heart cancer. http:// seer.cancer.gov/statfacts/html/soft.html. Accessed July 2015. Burningham Z, Hashibe M, Spector L, Schiffman JD. The epidemiology of sarcoma.Clin Sarcoma Res. 2012;2(1):14. Penel N, Grosjean J, Robin YM, Vanseymortier L, Clisant S, A...
Methods are lacking for the direct visualization of fibrillar collagen throughout the whole murine lung, a capability that would aid the understanding of lung fibrosis. We combined an optimized organ-level optical clearing (OC) approach with large-scale, label-free multiphoton microscopy (MPM) and ...
Note also positive immunoreaction of the cadherin-11 antibodies in the interstitial cells of the reticulum (mostly FRCs) that surrounds the sinus. Bar 50 µm Full size image So far, we have been unable to localize protocadherin-12, i.e. VE-cadherin-2 (Telo’ et al. 1998; Rampon et ...
Abstract Amniotic membrane (AM) or amnion is a thin membrane on the inner side of the fetal placenta; it completely surrounds the embryo and delimits the amniotic cavity, which is filled by amniotic liquid. In recent years, the structure and function of the amnion have been investigated, part...
cardiovascular system including a microwave antenna disposed within an antenna lumen, a plurality of fluid flow lumens substantially surrounding the antenna lumen and a balloon having an inflatable portion which partially surrounds the antenna lumen, the balloon being in communication with the fluid flow...