Biological tissues are composed of coded microstructures with different cell types. To mimic this structural complexity, we magnetically manipulated the assembly of two kinds of GUVs, i.e., 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl) (NBD PE) labeled ...
Tissues are complex mixtures of different cell subtypes, and this diversity is increasingly characterized using high-throughput single cell analysis methods. However, these efforts are hindered, as tissues must first be dissociated into single cell suspensions using methods that are often inefficient, lab...
The two main types of adipose tissue in mammals are brown adipose tissue (BAT) and white adipose tissue (WAT). BAT gradually disappears during growth and remains in the supraclavicular, periadrenal, and paravertebral regions of adult humans, and its main role is thermogenesis by uncoupling the ...
Post-mortem tissues samples are a key resource for investigating patterns of gene expression. However, the processes triggered by death and the post-mortem interval (PMI) can significantly alter physiologically normal RNA levels. We investigate the impact of PMI on gene expression using data from mu...
. The FAE of the DPP also contains M cells, but these are scattered between absorptiveenterocytes. The FAE of the proximal part of the CPP appears to be a transitional zone where the FAE of some domed villi are composed by pure M cells while others are composed of a mixture of M cells...
Alginate, composed of β-D-mannuronic and α-L-guluronic acid residues, is mainly found in brown seaweed and has been included in the U.S. Pharmacopoeia since 1938 [34,35]. In addition to the food industry, alginates are currently used in TE due to their excellent hydrophilicity, biosafe...
The mammalian circadian system is composed of multiple central and peripheral clocks that are temporally coordinated to synchronize physiology and behavior with environmental cycles. Mammals have three homologs of the circadianPeriodgene (Per1, 2, 3). While numerous studies have demonstrated thatPer1and...
central to the tissue's function and survival. This organization depends in part onpolarity, or the orientation of particular cells in their place. Of course, external signals from neighboring cells or from the extracellular matrix are also important influences on the arrangement of cells in a ...
The fibrous tissues of the spine are derived from sclerotome, an embryonic tissue composed of multipotent mesenchymal cells4,5. Previously, we showed that deletion of Tgfbr2 in Collagen2a (Col2a) expressing sclerotome led to significant defects in development of AF6,7. Others have shown that ...
Skin ulcers develop in the case of tissue disintegration and are caused by many different factors, from long-term pressure or lack of circulation and trauma [1]. The process healing of skin ulcers is composed of the coordination of three overlapping but distinct phases. This includes inflammation...