Objective Inadequate repair of the intervertebral disc (IVD) contributes to low back pain. Infiltrating immune cells into damaged tissues are critical mediators of repair, yet little is known about the identities, roles, and temporal regulation following IVD injury. By analyzing transcripts of immune ...
For his part, Rick Leach was no stranger to glory. Although the Philadelphia Phillies had selected him in the 11th round of the 1975 draft, Leach instead enrolled at the University of Michigan. He became the Wolverines starting quarterback in the second game of his freshman season and was ke...
Particularly interesting are the associations with OPRL1 and POMC, which play a role in modulating nociception and pain perception; in vitro studies in tissues from pregnant rats and humans suggest that the administration of nociceptin inhibits uterine contractions, mediated by the OPRL1 receptors19,...
conducted by a team of four to six people,involves attaching the tag,taking blood samples,and measuring the shark,all within a maximum of 12 minutes.If the shark shows any signs of pain,it is immediately sent back into the sea,regardless of whether all data has been collected.(大西洋鲨鱼...
Pain sensitivity increases with sleep disturbance under predictable chronic mild stress in mice Article Open access 09 July 2021 Individual sleep need is flexible and dynamically related to cognitive function Article 20 February 2024 Sleep contributes to preference for novel food odours in Drosophila...
It can also be performed with different types of medication: hyaluronic acid (HA), platelet-rich plasma (PRP), HA and PRP, corticosteroids (CS) and local anaesthetics (LA) (5, 6). The infiltrative treatment may be ineffective in reducing pain and improving function (7). Therefore, it is...
besides pain. Other key features include the ability to share information with doctors, nurses, and loved ones; customizable options like sound alerts; an automatic stopwatch function that starts measuring from zero at every birth instead of after the previous one finishes; ability to add reminders...
It often shows an unspecific clinical presentation characterized by widespread cramp-like abdominal pain, sometimes localized in the left abdominal quadrants. Fever and vomiting are rare at the beginning. An early diagnosis and management are crucial in both clinical types allowing the treatment of the...
E.T. Higgins Beyond pleasure and pain Am. Psychol., 52 (1997), pp. 1280-1300 Google Scholar Hilbe et al., 2013 C. Hilbe, M. Abou Chakra, P.M. Altrock, A. Traulsen The evolution of strategic timing in collective-risk dilemmas PLoS One, 8 (2013), p. e66490 CrossrefView in Scop...
Non-human animal studies outline precise mechanisms of central mu-opioid regulation of pain, stress, affiliation and reward processing. In humans, pharmacological blockade with non-selective opioid antagonists such as naloxone and naltrexone is typically used to assess involvement of the mu-opioid system...