A 2011 meta-analysis of 16 RCTs involved nearly 28,000 hospitalized nonsurgical, nonstroke patients with conditions including heart failure, respiratory disease, and infection.1 It examined the effectiveness of BID versus TID dosing of 5,000 units of subcutaneous unfractionated heparin (UFH) for ...
Dosing intervals for slow-release theophylline preparations depend on the rate of formulation absorption, the rate of patient elimination, and clinically acceptable fluctuations in serum concentration. Three products, two new to the United States market, have received approval by the Food and Drug Admin...
RESULTS. Receiving a UFH TID dosing regimen was significantly associated with a lower rate of PE when compared to receiving a UFH BID dosing regimen (尾 = 0.121, P = .044; TID rate = 0%, BID rate = 10.6%). UFH TID also showed a trend toward lower rates of DVT (尾 = 0.0893, P...
Protective efficacy of UV-4 dosing TID vs BID against influenza-infected mice.Eric J. StavaleHong VuAruna SampathUrban RamstedtKelly L. Warfield