肝缺血再灌注损伤(ischemia/reperfusion injury, IRI)常发生在肝移植、失血性休克、肝切除术后,临床上缺乏有效的治疗手段。肝脏IR损伤的病理过程以活性氧(ROS)的过量产生、线粒体功能障碍、钙超载、炎症细胞募集和促炎细胞因子的过量生成...
Journal of Hematology & Oncology (2023) 16:30 https://doi.org/10.1186/s13045-023-01429-1 Journal of Hematology & Oncology RESEARCH Open Access LCN2 secreted by tissue‑infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia...
tibiopedal accesspedal accessretrograde accessinfrapoplitealCritical limb ischemia (CLI) is associated with high rates of morbidity and mortality. Many patients with CLI are poor surgical candidates. Endovascular therapy has been shown to be an effective technique to improve arterial perfusion for ...
A multi-institution study led by the Prince of Wales Hospital and University of New South Wales, Australia, has found that everolimus-eluting resorbable scaffold treatment leads to better outcomes than angioplasty for chronic limb-threatening ischemia (CLTI) with infrapopliteal artery disease. Ad In ...
ischemia. Histopathologically, acute eosinophilic necrosis or “red dead” neurons were associated with FJ-C staining in both settings. Conversely, in mice affected by chronic cerebral microinfarcts due to tumor lysis syndrome as well as in a model of mitochondrial encephalopathy, FJ-C staining ...
The challenges of treating peripheral artery disease (PAD) and chronic limb-threatening ischemia (CLTI) require a comprehensive approach and robust endovascular toolbox. Endovascular specialists have become increasingly aggressive in treating this complex arterial disease to optimize wound healing, pre...
lactiplantibacillus < i > plantarum GL001 alleviates jejunal oxidative damage induced by intestinal ischemia-reperfusion injury by influencing jejunal tissue metabolism through the improvement of jejunal microbial composition. Life Sci 2023, 334. Download references Acknowledgements We...
Journal of Hematology & Oncology (2023) 16:30 https://doi.org/10.1186/s13045-023-01429-1 Journal of Hematology & Oncology RESEARCH Open Access LCN2 secreted by tissue‑infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia...
To investigate the potential impact of (CS/SP)2-LP on Aβ deposition in AD mice, dense amyloid plaques were visualized using Congo red staining. The number of brick-red plaques in the cortex and hippocampus was quantified in brain tissue (Fig.4A). Notably, no brick-red plaques were observ...
Chronic limb-threatening ischemia (CLTI) is a challenging disease to treat, requiring a tailored approach and comprehensive endovascular toolbox. The goal of treatment is to achieve wound healing, limb salvage, and improve quality of life. An innovative technology utilizing serrations has been develop...