Thyroxine-binding globulinhas only one binding site for thyroid hormones, and binds T4 with a higher affinity than T3. Because of its very high affinity for thyroid hormones, thyroxine-binding globulin, although present in serum at a much lower concentration than transthyretin or albumin, binds ...
Familial deficiency Clinical Background Thyroxine-binding globulin (TBG) is a glycoprotein produced in the liver. TBG binds both thyroxine (T4) and triiodothyronine (T3) with high affinity and accounts for 75% of plasma protein thyroxine-binding activity. Thus, an increase or decrease in its circu...
tetanus immune globulin a specific immune globulin derived from the blood plasma of human donors who have been immunized with tetanus toxoid; used in the prophylaxis and treatment of tetanus. thyronine-binding globulin (TBG) (thyroxine-binding globulin) an acidic glycoprotein that is the main binding...
(2000) Thyroxine-binding globulin as an indicator of body exposure to unfavorable environmental factors. Bulletin of Experimental Biology and Medicine 129 , 140-143 Online publication date: 1-Feb-2000. /Lapko AG, Golovatyi AS, Ermolenko MN, Milyutin AA (2000). Thyroxine-binding globulin as ...
Concentration of thyroxine binding globulin: value of direct assay. Brit. Med. J. 1977; 1 :485–487.Burr WA, Ramsden DB, Evans SE, Hogan T, Hoffenberg R. Concentration of thyroxine-binding globulin: value of direct assay.Br MedJ 1977; 1:485-8....
The principal transport protein for T 4 in human blood, thyroxine-binding globulin (TBG), binds T 4 with an exceptionally high affinity (K a � 10 10 M �1). Its homology to the superfamily of the serpins has recently been used in the design of chimeric proteins, providing experimenta...
Protein synthesis, and specifically thyoxine-binding globulin synthesis, were shown to continue throughout the incubation period, while cell survival remained high (75% excluded trypan blue after 6 h). Incubation medium, cytosol and a particulate fraction (extracted with digitonin) were analyzed for ...
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Two novel mutations leading to partial and complete thyroxine-binding globulin deficiency. 51 Symposium of the German Society for Endocrinology, Salzburg, Austria. f Also a silent mutation at codon 55: GCA > GCG. g Personal communication Joachim Pohlenz, Universitätsmedizin Mainz, Germany. No...
产品名称: THYROXINE-BINDING GLOBULIN, HUMAN .0 订购此产品 供应商: Merck 规格: *** 目录价: 3615 库存状态: 3周到货 CAS编号: 应用范围: 生化实验 种属来源: 相关信息: Thyroxine-Binding Globulin, Human Native, human thyroxine-binding globulin. Liver glycoprotein and a major thyroid hormone ...