People withGraves’ diseaseand thyroid cancer may also have an elevation in thyroid antibodies, including TPO and TG. However, the most common antibodies found in Graves’ disease are TSH receptor antibodies, including thyroid-stimulating immunoglobulin (TSI) — this marker is elevated in over 90 p...
Immunoglobulin sequence analysis of recombinant antibodies were performed using the IMGT tools V-Quest40 and DomainGapAlign,41 available at http://www.imgt.org. SPR analysis Kinetic and thermodynamic parameters for scFv binding to antigen were measured on a Biacore X100 instrument (Cytiva) at 25°...