Thyroid-stimulating hormone (TSH) is a glycoprotein produced by thyrotroph cells of the anterior pituitary gland, and consists of a heterodimer of two noncovalently linked subunits, α and β. Each subunit is encoded by a separate gene located on a different chromosome and is transcribed in a ...
-stimulating hormone then binds to TSH-Rs expressed on thyroid follicular cells, causing an increase in intracellularcyclic adenosine monophosphate(cAMP) and stimulation of second messenger systems, for the production of thyroid hormones,triiodothyronine(T3) andthyroxine(T4), in order to restore a...
Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To better understand the genetic contribution to TSH levels, we conduct a GWAS meta-analysis at 22.4 million genetic markers in up to 119,715 individuals and identify 74 genome-wide significant loci for TSH, of ...
TSH is a hormone made by the pituitary gland that tells the thyroid gland how much thyroid hormone to make. Read on to learn more about symptoms and treatments.
thyroid stimulating hormone (TSH, which is released by the pituitary gland) triiodothyronine (T3) thyroxine (T4) What Causes Thyroid Disease? There are many different reasons why either hyperthyroidism or hypothyroidism might develop. Currently, about 20 million Americans have some form of thyroid dise...
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Thyroid-Stimulating Hormone Thethyroid-stimulating hormone (TSH) test, and the T4 test, are the most commonthyroid function tests. The TSH test measures the level of circulating TSH, and is used to screen for, and diagnose thyroid disorders. It is also used for routine monitoring during hypothy...
Normal thyroid gland functioning depends upon iodide and stimuli from the hypothalamus (via thyrotropin-releasing hormone) and the adenohypophysis (via thyrotropin or thyroid-stimulating hormone). From: Vertebrate Endocrinology (Sixth Edition), 2021 ...
中文名称 Thyroid Stimulating Hormone 中文同义词 促甲状腺素国家标准品 英文名称 Thyroid Stimulating Hormone 英文同义词 CAS号 分子式 分子量 0 EINECS号 相关类别 Mol文件 Mol File 结构式 Thyroid Stimulating Hormone 性质 Thyroid Stimulating Hormone 用途与合成方法 安全信息 MSDS信息 Thyroid Stimulating...
Applying a uniform reference range across all adults for serum levels of thyroid stimulating hormone and thyroid hormones makes establishing a diagnosis of thyroid dysfunction challenging and could lead to potentially unnecessary treatment. For the results of thyroid function tests to be meaningful, the ...