Thyroid Receptor Interacting Protein 6doi:10.1007/978-3-642-16483-5_5811ZRP1 TRIP6; is a member of the zyxin family of proteins. Lipoma Preferred PartnerSpringer Berlin Heidelberg
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(TR), although cytosolic and membrane receptors also have been described on target cells. The most effective nuclear receptor complex for interacting with athyroid hormone response element (TRE)involves a heterodimer of occupied TR plus aretinoid X receptor protein (RXR). Homodimers of TR are ...
Define thyroid storm. thyroid storm synonyms, thyroid storm pronunciation, thyroid storm translation, English dictionary definition of thyroid storm. n. 1. Excessive production of thyroid hormones. 2. Excessive activity of the thyroid gland, characterize
Dysregulated protein synthesis has been shown to be one of the main characteristics of cancer [5]. To satisfy the internal oncogenic demands and external factors in the tumor microenvironment, cancer cells synthesized proteins rapidly and selectively [6]. Intracellular magnesium plays a positive role ...
[84]. MET belongs to the tyrosine kinase receptor protein family that regulates cell growth. It has been reported that there were circ-0079558 and MET up regulations in PTC tissues and cell lines. Circ-0079558 promoted the PTC cell proliferation and migration, while reduced apoptosis via miR-...
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For example, hsa_circ_0004789 (circRNA_102171) can directly bind to the CTNNBIP1 protein, blocking its interaction with the β-catenin/TCF3/TCF4/LEF1 complex. Consequently, the Wnt/β-catenin pathway is activated, promoting EMT in TC [41]. Similarly, hsa_circ_0088483 (circNEK6) promotes ...
That is, the “knock-in” of a mutant thyroid hormone receptor that can bind to T3 but not to DNA fails to reproduce the effect of low thyroid hormone.6 So, we know that thyroid hormone receptors bind to DNA and regulate gene expression because of these molecular studies that were ...
The thyroid hormone receptor/retinoblastoma-interacting protein 230 (TRIP230) was first identified through its interaction with RB and its ability to act as a TR coactivator in a thyroid hormone-dependent manner (Chang et al. 1997). RB was shown to inhibit this coactivator activity, thus definin...