Sap J , Munoz A , Schmitt J , Stunnenberg H and Vennström B ( 1989 ) Repression of transcription mediated at a thyroid hormone response element by the v- erb -A oncogene product . Nature , 340 , 242 – 244 .Sap, J., A. Munoz, J. Schmitt, H. Stunnenberg, and B. Vennstrom...
Thyroid hormone receptors are members of the nuclear receptor superfamily that includes the retinoic acid receptors, vitamin D3 receptor, and steroid receptors (Gronemeyer et al., 2004). Thyroid hormone receptors bind to specific DNA sequences called thyroid hormone response elements (T3REs) ...
Thyroid hormone stimulates renin gene expression through the thyroid hormone response ele- ment. Hypertension 2001;37:99-104.KOBORI H; HAYASHI M; SARUTA T.Thyroid hormonestimulates renin gene expression through the thyroid hormoneresponse element.Hypertension.2001.99-104...
The thyroid hormones, T3and T4, arise in thethyroid follicle cell. T3is the active form that moves into the nucleus of the liver cell, for example, and binds to thethyroid hormone receptorlocated on itsresponse elementand bound to acorepressorcomplex. When the hormone binds to the receptor,...
3,5,3′-Triiodothyronine T4: Thyroxine TAAR1: Trace amine-associated receptor 1 TH: Thyroid hormone Tn: Troponin TR: Thyroid hormone receptor TRE: Thyroid hormone response element TSH: Thyroid-stimulating hormone VSMC: Vascular smooth muscle cell...
我公司可提供各种标记物的该抗体:甲状腺激素受体α抗体Thyroidhormonereceptorα免疫标记 Phospho-PAK4(Ser99)免疫标记包括以下各类:AP ,APC , FITC ,Cy3 ,Cy5 , Biotin , PE-Cy3 ,PE-CY5 Alexa Fluor 350 , Alexa Fluor 488,PE ,HRP,Gold , Cy5.5 , Cy7 ,RBITC , PE-CY5.5 ,PE-CY7,Alexa Fluor 555...
This nuclear T3-receptor complex binds to thyroid hormone response elements on specific genes and regulates their transcription (genomic pathway)10. In short, there are two isoforms of THRα (1 and 2). THRα1 can bind to T3 and subsequently promotes its effects, whereas THRα2 lacks this ...
Zhang, Y., Yin, L. & Hillgartner, F. B. Thyroid hormone stimulates acetyl-coA carboxylase-α transcription in hepatocytes by modulating the composition of nuclear receptor complexes bound to a thyroid hormone response element.J. Biol. Chem.276, 974–983 (2001). ...
Transcriptional profiling of thyroid hormone disrupted animals coupled with a novel bioinformatics search revealed new thyroid response elements associated with genes previously unknown to be responsive to thyroid hormone. The work provides insight into thyroid response element sequence motif characteristics.Back...
The thyroid hormone receptor (TR) belongs to a large, evolutionarily conserved superfamily of nuclear receptors that function as ligand-regulated transcriptional activators or repressors. The major subtypes of TR, TRα1 and TRβ1, regulate the activity of numerous thyroid hormone-dependent physiological...