Jones K, Yaffe B & Chin W 1993 Regulation of thyroid hormone receptor -2 mRNA levels by retinoic acid. Molecular and Cellular Endocrinolgy 91 113-118.JONES KE, YAFFE BM, AND CHIN WW. Regulation of thyroid hormone receptor b-2 mRNA levels by retinoic acid. Mol Cell Endocrinol 91: 113-...
Dysregulation of the thyroid hormone receptor β (TRβ) is common in human cancers. Restoration of functional TRβ delays tumor progression in models of thyroid and breast cancers implicating TRβ as a tumor suppressor. Conversely, aberrant expression of the runt-related transcription factor 2 (Runx...
Thyroid hormone receptors (TRs) mediate hormone action by binding to DNA response elements (TREs) and either activating or repressing gene expression in the presence of ligand, T(3). Coactivator recruitment to the AF-2 region of TR in the presence of T(3) is central to this process. The ...
ARO-Cre/ThraAMI ↑ Dominant-negative thyroid receptor alpha in Sertoli and Leydig cells Mct8−/− ↑ No MCT8-mediated transport of thyroid hormones Dio3−/−/Thra−/− = No thyroid hormone clearance by DIO3 and no thyroid receptor alpha signaling Dio2−/− = No T4 to T3 ...
1. Thyroid hormone resistance with H435L mutation in exon 10 of thyroid hormone receptor β gene associated with Hashimoto's thyroiditis 甲状腺激素受体β基因第10外显子H435L突变致甲状腺激素抵抗并桥本甲状腺炎更多例句>> 2) thyroid hormone receptor β 甲状腺激素受体β 1. Objective To detect the ...
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Thyroid hormone receptor beta mutations in the 'hot-spot region' are rare events in thyroid carcinomas. J, de Castro IV, Soares P 2007 Thyroid hormone receptor {beta} mutations in the ``hot-spot region'' are rare events in thyroid carcinomas. J... AS Rocha,R Marques,I Bento,... -...
英文名字 Thyroid Hormone Receptor, 供应商 Abgent 产品货号 A-AN1103 产品报价 ￥3685/100 ul 产品说明书 点击查看 购买方式 产品新闻 背景资料 Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as ...
THRa重组蛋白是一种重要的蛋白质,它在许多生物体内起着关键的调节作用。THRa蛋白全称为Thyroid Hormone Receptor alpha,是一种核受体,在调节细胞的基因转录和表达方面发挥着重要作用。 目录号 PA2000-231 纯度:Greater than 85% as determined by SDS-PAGE. ...
Thyroid hormone receptors (TRs) are members of the nuclear receptor superfamily that mediate the pleiotropic activities of the thyroid hormone, T3, in differentiation, growth, and metabolism (Yen, 2001). From: Molecular and Cellular Endocrinology, 2009 ...