To investigate the effects of thyroid hormone and testosterone on 11β-hydroxysteroid dehydrogenase type 1 (11 β-HSD1), we measured changes in hepatic 11β-dehydrogenase activity and its mRNA levels in pubertal methimazole (MMI)-induced hypothyroid male rats following treatment with thyroxine ([T4...
TH action is mainly exerted by interaction with TH and thyroid hormone receptors (THRs) which are mainly of two types,THRαandTHRβ. THR is a nuclear receptor that requires TH as a ligand to be activated. THR binds to thyroid hormone response element (TRE) on the gene promoter and general...
1. The stimulations of DNA-dependent RNA polymerase in isolated rat-liver nuclei by thyroid hormone, human growth hormone and testosterone are compared. 2. Single or multiple administrations of growth-promoting doses of tri-iodo-l-thyronine, human growth hormone and testosterone stimulate the Mg(...
testosteroneThyroid hormones are important for growth and development of many tissues. Altered thyroid hormone status causes testicular abnormalities. For instance, juvenile hypothyroidism/neonatal transient hypothyroidism induces macroorchidism, increases testicular cell number (Sertoli, Leydig, and germ cells)...
Effects of the Pineal and Melatonin, With or Without Inhibitors of Thyroid Hormone/Testosterone, on Total Protein Contents of Serum, Liver and Muscle Tissues of Clarias batrachus during Different Phases of its Annual Gonadal Cyclepinealmelatonin
Growth hormone, secreted by the pituitary gland, controls growth of the body. Estrogen and testosterone control sexual development. Some of the hormones released in the brain, known as endorphins, act as natural painkillers. When the amounts of these or other hormones are abnormal, disease can ...
Huxley JS, Hogben LT (1922) Experiments on amphibian metamorphosis and pigment responses in relation to internal secretions. Proc R Soc B Biol Sci 93:36–53 CASGoogle Scholar Ichikawa K, DeGroot LJ (1987a) Purification and characterization of rat liver nuclear thyroid hormone receptors. Proc Nat...
► Thyroid hormone and testosterone may induce experimental myocardial hypertrophy by similar mechanisms involving mammalian target of rapamycin (mTOR), a serine-threonine kinase. ► Nuclear receptors for thyroid hormone and estrogen that are resident in the nucleus may also interact to modify ...
thy·roid-stim·u·lat·ing hormone (thī′roid-stĭm′yə-lā′tĭng) n.Abbr.TSH A hormone secreted by the anterior lobe of the pituitary gland that stimulates and regulates the activity of the thyroid gland. Also calledthyrotropin. ...
Serum testosterone was not different among groups at day 21, but significantly higher levels were seen in AMH+T3 compared to AMH++ mice at days 40 and 90. Similar pattern was seen for luteinizing hormone (LH)-stimulated testicular testosterone and androstenedione production in vitro. Findings ...