et al. Heterogeneity of thyroid cancer. Pathobiology 85(1–2), 117–129 (2018). Article PubMed Google Scholar Download references Acknowledgements The authors thank the Institute for Health Metrics and Evaluation (IHME) for data provision. Also, authors sincerely thank all the collaborators ...
Deeper understanding of cancer heterogeneity provides new opportunities for correctly streamlining the risk in patients, selecting markers for more effective therapeutic strategies, and leading the standard management approach for patients suffering from cancer to individualized treatment [6]. Many drugs can ...
In Blacks, the incidence of thyroid cancer was also statistically significantly higher in both Africans (RR 1.69, 99% FCI 1.34–2.13) and Caribbeans (RR 1.56, 99% FCI 1.25–1.93) but with no heterogeneity between these groups (P=0.5). The risk for thyroid cancer was highest in Chinese (...
However, most thyroid cancer research aggregates APIs into a single racial group despite their heterogeneity; it is well-documented that each API ethnic subgroup is distinct in terms of socioeconomic background, culture, and language [8]. In addition, the importance of disaggregating the API ...
compacted myocardium, and the most commonly used diagnostic criteria for adult LVNC patients are the Jenni criteria via transthoracic echocardiogram (TTE) and Petersen criteria via cardiac magnetic resonance (CMR) [18,19]. Due to the remarkable heterogeneity and wide spectrum of clinical presentations...
At first available follow-up (mean 8.2 (± 4.3) years), there was no difference in the primary outcome of BDI score between subclinical hypothyroidism and euthyroid controls (pooled mean difference (MD) 0.29, 95% CI − 0.17 to 0.76) with a low heterogeneity (I2 = 15.6%) ...
In the Italian population, Cochran’s Q of the MR-Egger and IVW methods showed heterogeneity in the association between sleep duration decrease and the risk of thyroid cancer. rs12607679 was an outlier SNP detected by MR-PRESSO. After removing this SNP, the difference was not statistically sign...
Sanders, Autoimmune myasthenia gravis: emerging clinical and biological heterogeneity, The Lancet Neurology, 2009, 8, 475-490.10.1016/S1474-4422(09)70063-8Search in Google Scholar [2] A. McGrogan, S. Sneddon, C.S. De Vries, The incidence of myasthenia gravis: a systematic literature review,...
In the general population the incidence of RET/PTC is ~10–25%, but it varies considerably among populations and could account for 50–70% of genetic alterations found in PTC samples (Table 2) [132]. This variability is likely due to different methods of detection; genetic heterogeneity of ...
et al. Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations. Int. J. Cancer 137, 1870–1878 (2015). 22. Casteel, D. E. et al. A DNA polymerase-{alpha}{middle dot}primase cofactor with homology to replication ...