Also called thyroid antibody test or thyroglobulin antibody test, this blood test checks your blood for thyroglobulin antibodies. Up to 10 percent of the U.S. population may have small amounts of this antibody in their blood all the time. Having a lot of these antibodies in your bloo...
13,18 Two alternate thyroglobulin assay methods can sometimes circumvent this problem: a traditional 2-antibody immunoassay and liquid chromatography-tandem mass spectrometry.19–21 In patients with thyroglobulin antibodies, serial monitoring of antibody levels in a single assay, can also sometimes be ...
Serum thyroglobulin antibody levels within or near to the reference range may interfere with thyroglobulin measurement High concentration of thyroglobulin antibodies (TgAb) is a major limiting factor of thyroglobulin measurements in patients with differentiated thyroid canc... Z Locsei,I Szabolcs,K Rác...
Purpose: Postoperative thyroglobulin (Tg) generally serves as a biomarker to monitor the recurrence or persistence of differentiated thyroid cancer (DTC), whereas it constrains to interference from anti-thyroglobulin antibody (TgAb). This study aimed to determine the value of postop...
When a high titer antibody is present, an appended comment reflecting the potential for positive or higher than reported Tg can help to ensure that the clinician is not falsely reassured by a low Tg level. 2.4.6.5 Reduction of thyroid hormone replacement doses in patients with thyroid cancer ...
A serum sample was taken in each trimester for measurement of Tg and Tg antibody (TgAb), in the Regional Laboratory for Endocrinology at the Royal Victoria Hospital Belfast. Both Tg and TgAb were measured using the Electrochemiluminescence immunoassay (ECLIA) on Elecsys and Cobas e immunoassay ana...
Additionally, a relevant problem in monitoring DTC patients is represented by the presence of thyroglobulin antibody (TgAb). TgAb is present in up to 15–25% of patients with DTC and may interfere on Tg immunoassays resulting in falsely low or undetectable Tg results [4]. In such cases, TgAb...
Tg levels were determined using a monoclonal antibody immunoradiometric assay (Cisbio Bioassays, Codolet, France). Washout CYFRA 21-1 levels were measured using an immunoradiometric assay kit (ELISA-CYFRA, Cisbio Bioassay, Codolet, France). The samples underwent a triple wash process, with the fi...
Subtyping of mAbs was performed using the IsoStrip Mouse Monoclonal Antibody Isotyping Kit (Roche, Indianapolis, IN, USA). Measuring human autoantibodies to TgAb Human TgAb was analyzed using a competitive assay (Brahms Kryptor, Henningsdorf, Germany) with a measuring range between 10 and 850 kU...
(4) absence of increased anti-Tg antibody levels15. Because the patients may receive further treatments if the Tg concentration kept increasing, the cases with serious comorbidities that may influence the uptake and/or excretion of131I were excluded. This study was approved by the Ethics Committee...