1. A small glandular organ that is situated behind the top of the breastbone, consisting mainly of lymphatic tissue and serving as the site of T cell differentiation. The thymus increases gradually in size and activity until puberty, after which it begins to atrophy. 2. A similar structure...
At present, the trend of opinion among the majority of immunological workers is that the thymus exercises control over all the immunological reactions of the body. Therefore, it is tempting to infer that the thymus is at least one of the contributing factors in antibody production. Nevertheless,...
RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook thymus (redirected fromThymus hormones) Dictionary Thesaurus Encyclopedia Related to Thymus hormones:adrenal gland hormones thymus [thi´mus] aductlessglandlyingintheuppermediastinumbeneaththesternum;itreachesitsmaximumdevelopm...
Similarly labeled spleen cells also accumulate in these areas but, in addition, are distributed at the periphery of splenic follicles and in the outer cortical zone of the lymph nodes. Many more spleen than thymus cells enter the lymphoid tissues and the spleen appears to be the primary target...
Current theories of negative selection state that this step is not possible for all putative autoantigens in the body, rather it applies to a selection of potentially-harmful specificities (in particular MHC antigens). In this way, the random pool of antigen recognition specificities of T-cells...
The thymus is a specialized primary lymphoid organ of the immune system. Within the thymus, T cells mature. Cells in the thymus can be divided into thymic stromal cells and cells of hematopoietic origin (derived from bone marrow resident hematopoietic stem cells)....
The thymus gland serves an essential role in providing an immune response to the body. The thymus produces hormones that stimulate the growth of the T...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your ...
As a conclusion, it is proposed that in addition to its central role in the regulation of the immune function, the thymus gland may extend its influence to nonimmunologic components of the body, including the neuroendocrine system. The early onset of thymus involution might, therefore, act as ...
The thymus plays a pivotal role in the development of the adaptive immune system, an important factor that separates higher vertebrates from the rest of the animal phyla. The development of functional T-cells from thymocytes is a crucial step in the development of a functional vertebrate immune ...
In cellular immunology the critical balance between effector and regulatory mechanisms is highlighted by serious immunopathologies attributable to mutations in Foxp3, a transcription factor required for a major subset of regulatory T (Tr) cells. Thus, many studies have focused on the developmental origi...