The myasthenic thymus demonstrates frequent abnormalities. Ten to 15% of myasthenics have a lymphoepithelial tumor and 70% of those without tumor demonstrate lymphoid follicular hyperplasia (LFH). In LFH, active germinal centers form between the cortex and the medulla, distending and sometimes disrupti...
FNC on compassionate use in the clinical treatment of COVID-19 was presented below. The clinical study was a randomized, single-arm, and multicenter trial. The primary goal of the trial is to learn whether oral FNC could inhibit the SARS-CoV-2 virus and shorten the disease course. A total...
Lead author Roberto Hernandez-Alejandro, MD, and colleagues note in their discussion that, as more centers begin to use this novel treatment approach, it will be important to establish prospective multicenter collaborations that will advance the understanding and refinement of the selection criteria....
Hyperplastic thymus is characterized by medullary B-cell infiltrates organized in ectopic germinal centers (GCs) forming follicles, which are surrounded by plasma cells and muscle-like myoid cells [7,8,9]. Myoid cells are suspected to participate in the loss of tolerance to muscle autoantigens ...