Herpes Simplex virus type 1 thymidine kinase (HSV-1 TK) phosphorylatesthymidine (dT) to thymidine monophosphate (dTMP), playing a key role inreactivation from the latency and replication phases of herpes simplex viruses. The antiviral agents acyclovir and ganciclovir act as substrates for HSV-1 ...
Herpes Simplex Virus Thymidine Kinase Gene-Transfected Tumor Cells; Sensitivity to Antiherpetic DrugsHerpes Simplex Virus Thymidine Kinase Gene-Transfected Tumor Cells; Sensitivity to Antiherpetic DrugsA series of antiherpetic 5-substituted 2-deoxyuridine derivatives (i. e. BVDU) and guanine derivatives ...
ImmunogenRecombinant African Swine Fever Virus Thymidine kinase (ASFV K196R) IsotypeIgG2a FormLiquid Purity> 95% PurificationPurified by Protein G affinity chromatography. StorageStore at 4 °C if the entire vial will be used within 1-2 weeks. For long-term storage, aliquot and store at -20 ...
Theherpes simplex virusthymidine kinase(HSV-TK) gene is the prototype of this class of enzymes in thenucleotide salvagepathway that has worked very well as aPET imagingreporter gene. It was first applied for this imaging purpose about 15 years ago (Gambhir et al., 1999, 1998; Tjuvajev et ...
virus-encoded thymidine kinase 青云英语翻译 请在下面的文本框内输入文字,然后点击开始翻译按钮进行翻译,如果您看不到结果,请重新翻译! 翻译结果1翻译结果2翻译结果3翻译结果4翻译结果5 翻译结果1复制译文编辑译文朗读译文返回顶部 病毒编码的胸苷激酶 翻译结果2复制译文编辑译文朗读译文返回顶部...
THYMIDINE KINASE DELETED BOVINE HERPES-VIRUS-1 MUT 专利名称：THYMIDINE KINASE DELETED BOVINE HERPES-VIRUS-1 MUTANTS 发明人：MALON KIT,SAUL KIT 申请号：AU6489986 申请日：19861105 公开号：AU598764B2 公开日：19900705 专利内容由知识产权出版社提供 摘要：Bovine herpesvirus type 1 (infectious bovine rhino...
An enzymatic assay for herpes virus simplex type 1 thymidine kinase (HSV-TK) that was sensitive enough to quantitate intracellular levels of enzyme transiently expressed after transfection of HSV-TK vectors into TK-deficient cells using the DNA-calcium phosphate coprecipitation technique is described. ...
Gene therapy has many potential applications in central nervous system (CNS) disorders, including the selective killing of tumor cells in the brain. A rat brain tumor model was used to test the herpes simplex virus (HSV)-thymidine kinase (TK) gene for it
Almost all DNA viruses e.g., bacteriophages, vaccinia viruses, pox viruses and herpes viruses code for enzymes with thymidine kinase activity. However, the herpes virus thymidine kinases belong to the same enzyme family as dCK and not the TK1 family as described below. The expression of TK1 ...
In one embodiment, a polynucleotide sequence encodes a mutated form of thymidine kinase from a human herpes simplex virus (HSV-TK) comprising 2, 3, 4, 5, 6, 7, 8, 9, 10 or more modifications. In another embodiment, a polynucleotide sequence encodes a mutated form of thymidine kinase from...