The differentiation of mouse neurons is a complex process involving cell maturation and branching, occurring during both, embryonic development and differentiation in vitro. To study mouse neuronal morphology, we used the Thy1 YFP-16 mouse strain. Although this mouse strain was described over twenty ...
genic mouse strain in tumourigenesis, wound-healing and inflam- mation studies. Results The analysis of the transgenic mice under fluorescent microscope revealed, as expected, the expression of the transgene was restricted to the brain and the nerves; no other tissues proved to be fluorescent, eithe...
Introduction: This study was based on the mouse strain B6.Cg-Tg(Thy1-YFP)16Jrs/J which under the control of Thy1 gene promoter expresses yellow fluorescent protein (YFP) in all parts of neurons. In this study, we have determined and compared expression pattern of: 1) Thy1 - YFP positiv...
PURPOSE. We characterized fluorescent bone marrow cells (YFP+ BMCs) in the thy1-YFP mouse and determine if they promote trigeminal ganglion (TG) cell neuri... J Sarkar,S Chaudhary,SH Jassim,... - 《Investigative Ophthalmology & Visual Science》 被引量: 29发表: 2013年 Excitotoxicity upregulat...
Neural stem cells isolated from Thy1 YFP-16 mouse strain transplanted near hippocampus of the healthy and stroke-affected brain were distinguishable by YFP fluorescence. They differentiated into mature neurons and were detectable even 14 weeks after transplantation, the end point of our experiment. In...
In summary, the Thy1.2 YFP-16 mouse expresses robust YFP expression in only a subset of sensory neurons. But this mouse model is not suitable for the study of nociceptive nerves or the function of such nerves in pain and neuropathies.PLoS ONE (v.1;2006)Thomas E. Taylor-ClarkKevin Y. ...
Results :The Thy1-YFP-H mouse expresses YFP in ON, OFF and ON-OFF RGCs (Fig.1A). The AUC calculated from Sholl profiles was 37.1% and 25.6% higher in ON RGCs compared to OFF and ON-OFF cells, respectively (Fig.1B). Whereas there was only a 9.2% AUC difference between OFF and...
Thy1-YFP mouseConditioning injuryWe evaluate axonal regeneration in Thy1-YFP mice via in vivo transcutaneous imaging. Animals undergo saphenous nerve crush, various FK-506 regimens, and in vivo imaging. Animals with central GDNF overexpression are assessed. Daily FK-506 with preload accelerates ...
Using this dual fluorescent mouse strain, we were able to visualize the networks of nervous and vascular tissue simultaneously in various organ systems both in the physiological state and after injury. Using ex vivo high-resolution imaging in this dual fluorescent strain, we characterized the ...
Shank 1 immunoreactivity is expressed solely within cone terminals of the mouse thy-1.2 YFP 16 line retina.Salvatore L. Stella JrAlejandro VilaAlbert Y. HungMichael E. RomeUyenchi HuynhMorgan ShengHansJuergen KreienkampNicholas C. Brecha