The outcomes data from the first available time point identified as a primary end point from each trial were incorporated into our primary analysis, noting the acute nature of intervention with thrombolytics. Several prespecified subanalyses were performed as described in the next section. Each trial...
The additional value of IVT could not be examined in the Extending the Time for Thrombolysis in Emergency Neurological Deficits–Intra-arterial (EXTEND-IA) and Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke (SWIFT PRIME) because treatment ...
摘要: would suggest that the majority of people are reasonably certain within this relatively short time frame. If uncertainty does exist, then it would be unreasonable to administer thrombolytic therapy, particularly if the time after stroke onset was approaching 3 hours.关键词:...
This case has been presented as poster abstract at the 121st Meeting of the British Neuropathological Society [26]. Case presentation A 55-year-old man was admitted to hospital as a stroke call, presenting with sudden-onset left sided cheek, arm and hand sensory loss, visual blurring, and...
In particular, the influence of coronary thrombolysis on both acute and long-term mortality, the critical time interval for the intervention to be initiated, the best drug, its optimal dose and the route of administration, and the management of the residual stenosis remain unknown.These keywords ...
We performed a cost-effectiveness analysis to quantify the health effects and economic outcomes associated with the use of thrombolytic therapy. Specifically, we compared treatment with alteplase plus heparin vs heparin alone as primary therapy in hemodynamically stable patients with acute pulmonary embolism...
Warfarin is a commonly used oral anticoagulant, and has well-established clinical efficacy. However, it has a narrow therapeutic window, and a mode-of-act... GJ Merli,G Tzanis - 《Journal of Thrombosis & Thrombolysis》 被引量: 457发表: 2009年 Time to reperfusion: The critical modulator in...
Factor XI (FXI), a 160-kDa glycoprotein serine protease, exists as a dimer with two identical subunits, each comprising 607 amino acids and linked by disulfide bonds. Each polypeptide is composed of a C-terminal light chain of 35 kDa, housing the trypsin-like catalytic domain, and an N-te...
An Analysis of Time Delays Preceding Thrombolysis for Acute Myocardial Infarction For a patient to derive maximal benefit from intravenous thrombolytic therapy for acute myocardial infarction, early treatment is essential. As part of the... Sharkey,W Scott - 《Jama the Journal of the American Medical...
None of these events was adjudicated as being clearly related to STEMO-specific interventions by the safety board (1 respiratory and 1 neurological worsening during transportation were judged as possibly related to STEMO intervention). There were no breakdowns of the CT scanner but 1 breakdown of ...