Thrombocytopenia may be present at birth due to intrauterine disorders, but is most commonly detected after birth following bacterial infection. There is no consensus regarding optimal hemoglobin and platelet thresholds for transfusion. An increasing number of studies suggest that restrictive transfusion ...
However, ultimately, the majority of pathogenic genetic variants may present as isolated thrombocytopenia (Table 1). Genetic diagnosis, cost, and ethical considerations Since the application of next-generation sequencing (NGS) to patients with inherited thrombocytopenias, there has been an explosion of ...
Clinically, HIT may manifest as skin lesions at heparin injection sites or by acute systemic reactions (eg, chills, fever, dyspnea, chest pain) after administration of an intravenous bolus of heparin and may present in the form of thrombotic complications along with thrombocytopenia. The development...
In the present study, we investigated plasma levels of interleukin (IL)-12 and transforming growth factor (TGF-尾1) in malaria patients as these two cytoki... SC Chaiyaroj,ASM Rutta,K Muenthaisong,... - 《Acta Tropica》 被引量: 282发表: 2004年 ...
can all cause low platelet counts. Because platelets play a vital role in blood clotting, low levels may increase the risk of bleeding. Platelet counts below 50,000/mm3increase the risk of hemorrhage with minor trauma; spontaneous bleeding can occur when less than 20,000 are present in a mil...
BACKGROUND The May-Hegglin anomaly is among a group of genetic disorders known as MYH9-related disease.Patients with inherited platelet disorders such as M... B Jiang,M Hartzell,S Yu,... - 世界血液学杂志 被引量: 0发表: 2023年 Identification of a Novel Gene Mutation in a Chinese Pedigree...
Based on our findings, it may be worthwhile to order an assay for platelet count among elderly patients presenting to ED for medical illnesses, for gauging their AKI risk. Avoidance of nephrotoxin exposure could also be considered for elderly patient who present to the ED with thrombocytopenia. ...
May—Thurner syndrome is an uncommon process in which the right common iliac artery compresses the left common iliac vein, resulting in left iliofemoral deep vein thrombosis and severe leg edema. We report the case of a 41-year-old female who presented with severe left leg edema present for...
Treatment with INF-± is frequently complicated by adverse effects, which may rarely be immune mediated. We report 2 patients with Ph+ chronic myeloid leukemia (CML) who developed autoimmune thrombocytopenia while receiving months of treatment with INF-±. This complication responded well to ...
1 did not bind to TPO reproducibly on Western blots, probably due to the lesser titer of antibody present or the fact that much of the antibody existed as an IgG-TPO complex. Because PEG-rHuMGDF contains only the first 163 of the 332 amino acids in rHuTPO, the finding that rHuTPO and...