Single-molecule localization microscopy is a powerful tool for visualizing subcellular structures, interactions and protein functions in biological research. However, inhomogeneous refractive indices inside cells and tissues distort the fluorescent signa
Human GLTP: Three Distinct Functions for the Three Tryptophans in a Novel Peripheral Amphitropic FoldHumansCell MembraneTryptophanGlycolipidsSpectrometry, FluorescenceCircular DichroismProtein Structure, TertiaryMutationMutagenesisCarrier ProteinsHuman glycolipid transfer protein (GLTP) serves as the GLTP-fold ...
HO-PEG-FA has good water solubility and cell membrane permeability. HO-PEG-FA can also be used to label biomolecules such as proteins, nucleic acids, etc. By combining with these biomolecules, localization, tracking, and quantitative analysis of biomolecules can be achieved. 中文名:羟基聚乙二醇叶...
These systems have been used to visualize the cellular basis of epithelial morphogenesis, to test the roles of specific genes in regulating cell behaviours within epithelial tissues and to elucidate the contribution of microenvironmental factors to normal and disease processes. Collectively, these novel ...
It is thus hypothesised that it is the ratio of short:long Homer isoforms that is of functional importance, particularly in maintaining calcium homeostasis (Kaja et al., 2013), and that the functions of long and short Homer isoforms vary according to brain region and cell-type (Ango et al....
Effects of LAB-fermented proteins on the proliferation of RAW 264.7 osteoclasts and MC3T3-E1 osteoblasts To determine the optimal dosage for in vitro assays, the cell viability of RAW 264.7 and MC3T3-E1 cells treated with different dosages of LAB-fermented proteins were measured using the MTT ass...
To date, there have not been great breakthroughs in immunotherapy for HER2 positive breast cancer (HPBC). This study aimed to build a risk model that might contribute to predicting prognosis and discriminating the immune landscape in patients with HPBC.
In class I fusion proteins it is generally at the N-terminus, and it is termed fusion “peptide” because it is not rigidly connected to the rest of the ectodomain and adopts a particular structure upon insertion into lipid bilayers (Apellaniz et al., 2014). In classes II and III, ...
Scale bar: 0.5 μm (G) Enlarged TEM image of XEN cell spurting proteins. Heatmap analyses confirmed that gene sets involved in ‘vesicle-mediated transport’ were dramatically upregulated in XEN cells compared with that in ESCs and TSCs. Scale bar: 0.5 μm. ESC, embryonic stem cells; TSC...
The last decade has seen an increased exploration into the roles of TM4SF1 to further understand its functions in cancer progression and associated molecular mechanisms. Section 3.1, Section 3.2, Section 3.3, Section 3.4, Section 3.5 and Section 3.6 outline the regulatory roles of TM4SF1 in the...