In addition, the conserved elements of these machineries, transiently or permanently exposed on the virion surface, provide clinical targets for development of inhibitors (antivirals) and immunogens (vaccines) (Blumenthal and Dimitrov, 2007, Doms and Moore, 2000, Eckert and Kim, 2001, Forssmann ...
The advent of SARS-CoV-2 vaccines has significantly slowed down the spread of the virus, but there is still no cure to treat the infection once it is contracted, and there is an urgent request for innovative prophylactic approaches. Peptides represent a valid and safe alternative for treating...
In addition, it is desirable to minimize the vaccine immunization differential, represented by the last term of the functional, so that there is not a very sudden variation in the number of vaccines given from one week to the next. 8.2.1. Results for Vaccination Control The simulation paramete...