DETAILED ANALYSIS OF TUMOR INFILTRATING LYMPHOCYTES IN THREE AGE CATEGORIES OF BREAST CANCER PATIENTS: CORRELATION WITH SYSTEMIC IMMUNOSENESCENCE/FRAILTY MARKERSdoi:10.1016/S1879-4068(19)31320-7L. BerbenH. WildiersC. KenisB. DalmassoS. Hatse
The presence of circulating HPV-reactive T-lymphocytes and of tumour-infiltrating cytotoxic T-lymphocytes have been associated with lower N-stage and improved prognosis in cervical cancer patients33,34,35,36,37,38,39,40,41. We used DNA methylation data to compare the cellular composition of TCGA...
Cdk5 is a proline-directed serine/threonine protein kinase that governs a variety of cellular processes in neurons, the dysregulation of which compromises normal brain function. The mechanisms underlying the modulation of Cdk5, its modes of action, and i
The thymus is responsible for programming the immune system9. Specifically, by GW 12-13 this organ starts producing T-cells (or thymic-dependent (T) lymphocytes, whose precursors originate from the bone marrow), which form part of the adaptive immune system, providing the body with cell-mediate...
All the sensitizers tested (DNCB, OXA and TDI) induced significant up-regulation of Psme4, which is associated with DNA replication; Tfdp1, which is related to cell cycle regulation; and Dut, which is involved in pyrimidine metabolism. Specific changes were also shown in functional categories ...
mitochondrial dysfunction, and oxidative stress. The Cdk5 substrates discussed in this review and their functional categories are listed in Table1, and the reader is referred to several excellent reviews with a more comprehensive list of known Cdk5 substrates [28,29,30,31,32,33,34,35,36,37]....
Differentiation of lymphocytes is frequently accompanied by cell cycle changes, interplay that is of central importance for immunity but is still incompletely understood. Here, we interrogate and quantitatively model how proliferation is linked to differ
Categories of customers with febrile illness going to the paediatric disaster division MAIN OUTCOME MEASURES Non-medical out-of-pocket costs for the entry had been projected by members hepatic hemangioma including transportation, meals and beverages, childcare, miscellaneous expenses and loss of profits....
6B). These data showed that the important biological processes included T cell activation, lymphocyte proliferation, regulation of T cell activation, lymphocyte differentiation and positive regulation of lymphocyte activation. In addition, the enriched cellular component and molecular function categories are ...
COORDS format using the show-coords command with ‘-clrTH’ option. Short mate-pair reads were classified into four categories (mp, pe, se, and unknown) using NxTrim software54(ver. 0.4.3), and the resulting set of reads with the correct mate-pair orientation (mp) were mapped using ...