THP-1 cells are a monocyte-like cell line derived from a patient with acute monocytic leukemia and unlike other leukemic cell lines has a normal diploid ka... HB Fleit,CD Kobasiuk - 《Journal of Leukocyte Biology》 被引量: 148发表: 1991年 Activation of Fc R I on human monocyte cell li...
Porphyromonas gingivalis‐induced inflammatory responses in THP1 cells are altered by native and modified low‐density lipoproteins in a strain‐dependent ... Porphyromonas gingivalis‐induced inflammatory responses in THP1 cells are altered by native and modified low‐density lipoproteins in a strain‐...
Elevated levels of cytokines were secreted by cells in a homogenous differentiation state. In addition, it was determined that the assay performs best when using cells at a concentration of (2.5–5) × 105 cells mL1. CONCLUSION An assay was developed suitable to distinguish the immunomodulatory ...
Results ResistinmRNAwas positively associated with immunoglobulin heavy chain‐binding protein (BiP) orCAAT/enhancer binding protein‐α homologous protein (CHOP)mRNAin human isolated monocytes. InTHP‐1 cells, lipopolysaccharides increasedmRNAof BiP, pancreatic endoplasmic reticulum eukaryotic initiation factor...
THP-1 cells can be easily differentiated into macrophage-like cells with increased adherence, loss of proliferative activity, and CD14+/CD11b+ phenotype [22]. In this work, we aimed to evaluate the effect of leukocyte dialyzable extract, Transferon®, on CD80 and CD86 surface expression as...
In summary, we show that P.?gingivalis is capable of inducing pro‐inflammatory responses in THP 1 cells, and native and modified LDL could alter these responses in a dose‐ and strain‐dependent manner. Strain‐dependent differences in THP 1 cell responses could be due to the effect of P....
P2Y 12 P2Y 12 12 receptor modulation of ADP ADP ‐evoked intracellular Ca 2+ Ca 2+ 2+ signalling in THP‐1 human monocytic cells 喜欢 0 阅读量: 9 作者: Micklewright,J,J,Layhadi,J,A,Fountain,S,J 摘要: Background and Purpose The G i ‐coupled, ADP‐activ ...