When cocultured with a target cell and relevant antibody, the ADCP Reporter Bioassay Effector Cells (THP-1) bind the Fc domain of the antibody, resulting in promoter-driven luminescence. This Technical Manual is relevant for Cat.# JA9411 and JA9415; JA9511 and JA9515 (Korea); JA9611 and ...
ADCP can be a tool to assess the efficacy of vaccine-induced antibodies, in addition to measuring the neutralizing ability of antibodies. Here, we developed and validated an efficient and high-throughput plate-based flow cytometric assay to measure ADCP of IEs using the human monocytic THP-1 ...
ADCP contributes to the antitumor response by enhancing the ability of phagocytic cells to engulf cancer cells upon antibody binding. We aimed to engineer CD147KO THP-1 cells and evaluated their differentiation properties compared to the wild type. A humanized anti-CD147 antibody, HuM6-1B9, was...