AtECB1/MRL7, a thioredoxin-like fold protein with disulfide reductase activity, regulates chloroplast gene expression and chloroplast biogenesis in Arabidopsis thaliana . Molecular Plant . 2014; 7 : 206–217. doi: 10.1093/mp/sst092Yu, Q. B., Ma, Q., Kong, M. M., Zhao, T. T., Zhang...
The invention features compositions based on thioredoxin-like fold protein domains described as engineered thioredoxin-like fold proteins (ETRXs). These proteins include one or more artificially diversified thioredoxin-like fold protein domains; each dom
2 Several cytokine-like factors are identical or related to thioredoxin. Thioredoxin has been reported to have chemokine-like activity (see [31] in this volume3). Mammalian thioredoxin 2 (thioredoxin 2) has high homology with thioredoxin and has an active site Cys-Gly-Pro-Cys with thiol-...
The iodothyronine selenodeiodinases are thioredoxin-fold family proteins containing a glycoside hydrolase clan GH-A-like structure. The three iodothyronine selenodeiodinases catalyze the initiation and termination of thyroid hormone effects in vertebrates. Structural analyses of these p... I Callebaut,C ...
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Besides the role of ADAM proteins in the secretion of TRXs and TRX80, it is important to consider the possible involvement of proteins like those involved in the oxidative folding of proteins as secretion mechanisms [36,37]. Since the secretion of TRXs is dependent on factors, such as the ...
Fold-increase in Caspase-3 activity was determined by comparing these results with the level of the control group. Background reading from cell lysates and buffers had been subtracted from the readings of both induced and non-induced samples before calculating the fold increase in the Caspase-3 ...
Interestingly, the Txnrd1−/− MEFs seemed to differentiate into brown-like or beige adipocytes, as reflected by increased UCP1 expression3,50. Thus, TrxR1 may possibly also play specific roles in regulation of white vs beige adipocyte differentiation, which should clearly be studied further....
(Biterovaet al., 2005). In addition to thioredoxin, and like its cytosolic counterpart, TrxR2 is able to reduce several different unrelated substrates such as DTNB (5,5′-dithiobis(2-nitrobenzoic acid)), selenite, and alloxan (Rigobelloet al., 1998). It has also been identified in many...
The serine protease domain of murein urokinase (ΔA-uPA) requires six disulfide bonds to fold into an active conformation (40). Like APΔ2-22, when ΔA-uPA is expressed in the cytoplasm of wild-type cells, it cannot form its native disulfide bonds and, therefore, is not enzymatically ...