Thiazolidinediones are a new class of drugs for the treatment of type 2 diabetes, and act by improving insulin sensitivity in adipose tissue, liver and skeletal muscle. Rosiglitazone and pioglitazone are registered for use in monotherapy, and in combination with sulfonylureas and metformin. ...
Mode of action of peroxisome proliferators as hypolipidemic drugs. Suppression od apolipoprotein C-III. J Biol Chem 1995;270:13470-5. 7.Galli A, Stewart M, Dorris R, et al. High-level expression of RXRalpha and the presence of endogenous ligands contribute to expression of a peroxisome ...
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According to the latest information from the 41~(th) EASD Annual Meeting in 2005,we summarize some noval therapeutic drugs for diabetes,such as non-thiazolidinedione insulin sensitizer incretins,DPP-IV inhibitors,new insulin analogue. 结合2005年欧洲糖尿病年会的最新信息,对近年来已上市和正在试验及研...
Twitter Google Share on Facebook thiazolidinediones Dictionary Acronyms Related to thiazolidinediones:Biguanides,meglitinides A class of drugs used to combatINSULIN RESISTANCEin patients with Type 2DIABETES. These drugs are insulin sensitizing agents and act by binding selectively to preoxisome-proliferator...
Thiazolidinediones multum therapeutic drug class usage statistics for the United States (2013 - 2022). Statistics include a comparison of all drugs within the multum therapeutic drug class of Thiazolidinediones.
2.According to the latest information from the 41~(th) EASD Annual Meeting in 2005,we summarize some noval therapeutic drugs for diabetes,such as non-thiazolidinedione insulin sensitizer incretins,DPP-IV inhibitors,new insulin analogue.结合2005年欧洲糖尿病年会的最新信息,对近年来已上市和正在试验及研...
Antidiabetic biguanides/thiazolidinediones (also known as glitazones) are oral antidiabetic drugs used with a proper diet and exercise to control high blood sugar in people with type 2 diabetes mellitus (T2DM).
The thiazolidinediones troglitazone, rosiglitazone and pioglitazone reduce insulin resistance by altering gene expression involved in glucose and lipid metabolism, via binding to peroxisome proliferator-activated receptor γ. Thiazolidinediones show additive therapeutic effects when combined with metformin, a sulp...
Antidiabetic (Type 2) drugs enhancing sensitivity to insulin. They are agonists and ligands to PPAR-γ receptors of adipocytes. They may have modest beneficial effects on the level of the desirable high-density lipoprotein (see Fig. T46). diabetes, PPAR, high-density lipoprotein, adipocytes, ...